PDCD1

Gene Symbol PDCD1
Entrez Gene 5133
Alt Symbol CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Species Human
Gene Type protein-coding
Description programmed cell death 1
Other Description programmed cell death protein 1|protein PD-1|systemic lupus erythematosus susceptibility 2
Swissprots O00517 Q8IX89 Q15116
Accessions AAC41700 AAC51774 AAN64003 ABK41899 CBX51254 EAW71298 Q15116 AI928135 AK313848 BAG36577 AY206416 AAO25116 AY238517 AAO63583 AY322430 AAP85379 BC074740 AAH74740 CR988122 U64863 AAC51773 XM_006712573 XP_006712636 XM_006724986 XP_006725049 NM_005018 NP_005009
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. {ECO:0000269|PubMed:21276005}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways T cell receptor signaling pathway, Cell adhesion molecules (CAMs)

Pdcd-1 CRISPR/Cas9 KO Plasmid (h) - sc-403008 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 HDR Plasmid (h) - sc-403008-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 Double Nickase Plasmid (h) - sc-403008-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 Double Nickase Plasmid (h2) - sc-403008-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 CRISPR Activation Plasmid (h) - sc-403008-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 CRISPR Activation Plasmid (h2) - sc-403008-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 Lentiviral Activation Particles (h) - sc-403008-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 Lentiviral Activation Particles (h2) - sc-403008-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1 siRNA (h) - sc-44002 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pdcd-1 shRNA Plasmid (h) - sc-44002-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pdcd-1 shRNA (h) Lentiviral Particles - sc-44002-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PD-1 RNAi - H00005133-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU146521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16513 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16513 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PDCD1 siRNA (Human) - CRH3414 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PDCD1 (NM_005018.2) - SHH372140 from Creative biogene

Category siRNA
Species Reactivities Human

Human PD1 siRNA - orb263916 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDCD1 shRNA Plasmid (Human) - CHH3414 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PDCD1 miRNA 3'UTR clone - MiUTR1H-07692 from Creative biogene

Species Reactivities Human
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