ZC3H12D

Gene Symbol ZC3H12D
Entrez Gene 340152
Alt Symbol C6orf95, MCPIP4, TFL, dJ281H8.1, p34
Species Human
Gene Type protein-coding
Description zinc finger CCCH-type containing 12D
Other Description Zinc finger CCCH domain-containing protein 12D|p34|probable ribonuclease ZC3H12D|transformed follicular lymphoma|tumor suppressor TFL
Swissprots Q6ZRW2 B9ZZQ0 B7WNU7 B9ZZP9 B2RXF4 A1L178 A2A288
Accessions A2A288 CAX11886 CAX11887 AB458221 BAH28268 AB458222 BAH28269 AK090441 BAC03422 AK127932 BAC87196 BC127762 AAI27763 BC157832 AAI57833 NM_207360 NP_997243
Function May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation. {ECO:0000269|PubMed:17210687, ECO:0000269|PubMed:19531561, ECO:0000305}.
Subcellular Location Isoform 1: Cytoplasm. Note=Localized as discrete granules. Colocalized with mRNA-processing body markers, AGO2 and DCP1A, but not with a stress granule maker, TIA1, in the cytoplasm.
Tissue Specificity Expressed in normal human lymphocytes but defective in some leukemia/lymphoma cell lines. {ECO:0000269|PubMed:19531561}.

ZC3H12D Antibody Blocking Peptide - LS-E30898 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

ZC3H12D Antibody Blocking Peptide - LS-E24142 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ZC3H12D control peptide - AP26202CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

ZC3H12D Peptide - 5679P from ProSci

Category Peptide
Species Human
Western blot analysis of ZC3H12D in THP-1 cell lysate with ZC3H12D antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

ZC3H12D fusion protein - Ag21770 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human Probable ribonuclease ZC3H12D(ZC3H12D) - CSB-YP026357HU CSB-EP026357HU CSB-BP026357HU CSB-MP026357HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Probable ribonuclease ZC3H12D (ZC3H12D), Recombinant Protein - MBS1134645 from MyBioSource

Category Protein
Prices $1,375.00, $1,835.00
Sizes 1 mg (E-Coli), 1 mg (Yeast)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

ZC3H12D Recombinant Protein Antigen - NBP1-91249PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

ZC3H12D Peptide, Human - M34GP17713H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
Search more