ZC3H12D

Gene Symbol ZC3H12D
Entrez Gene 340152
Alt Symbol C6orf95, MCPIP4, TFL, dJ281H8.1, p34
Species Human
Gene Type protein-coding
Description zinc finger CCCH-type containing 12D
Other Description Zinc finger CCCH domain-containing protein 12D|p34|probable ribonuclease ZC3H12D|transformed follicular lymphoma|tumor suppressor TFL
Swissprots Q6ZRW2 B9ZZQ0 B7WNU7 B9ZZP9 B2RXF4 A1L178 A2A288
Accessions A2A288 CAX11886 CAX11887 AB458221 BAH28268 AB458222 BAH28269 AK090441 BAC03422 AK127932 BAC87196 BC127762 AAI27763 BC157832 AAI57833 NM_207360 NP_997243
Function May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation. {ECO:0000269|PubMed:17210687, ECO:0000269|PubMed:19531561, ECO:0000305}.
Subcellular Location Isoform 1: Cytoplasm. Note=Localized as discrete granules. Colocalized with mRNA-processing body markers, AGO2 and DCP1A, but not with a stress granule maker, TIA1, in the cytoplasm.
Tissue Specificity Expressed in normal human lymphocytes but defective in some leukemia/lymphoma cell lines. {ECO:0000269|PubMed:19531561}.

ZC3H12D CRISPR/Cas9 KO Plasmid (h) - sc-410424 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D HDR Plasmid (h) - sc-410424-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D Double Nickase Plasmid (h) - sc-410424-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D Double Nickase Plasmid (h2) - sc-410424-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D CRISPR Activation Plasmid (h) - sc-410424-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D CRISPR Activation Plasmid (h2) - sc-410424-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D Lentiviral Activation Particles (h) - sc-410424-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZC3H12D Lentiviral Activation Particles (h2) - sc-410424-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN23097 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23097 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZC3H12D siRNA (Human) - CRJ7328 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZC3H12D - MBS8235952 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Zc3h12d (NM_207360.2) - SHH449400 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZC3H12D siRNA - orb277829 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZC3H12D shRNA Plasmid (Human) - CHJ7328 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZC3H12D miRNA 3'UTR clone - MiUTR4H-TG10009 from Creative biogene

Species Reactivities Human
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