SSRP1

Gene Symbol SSRP1
Entrez Gene 6749
Alt Symbol FACT, FACT80, T160
Species Human
Gene Type protein-coding
Description structure specific recognition protein 1
Other Description FACT 80 kDa subunit|FACT complex subunit SSRP1|FACTp80|chromatin-specific transcription elongation factor 80 kDa subunit|cisplatin-DNA SSRP|facilitates chromatin remodeling 80 kDa subunit|facilitates chromatin transcription complex 80 kDa subunit|facilitates chromatin transcription complex subunit SSRP1|hSSRP1|high mobility group box|recombination signal sequence recognition protein 1|structure-specific recognition protein 1
Swissprots Q5BJG8 Q08945
Accessions CCQ43203 EAW73734 EAW73735 Q08945 AB209132 BAD92369 BC005116 AAH05116 BC091486 AAH91486 DQ893659 ABM84585 DQ895832 ABM86758 M86737 AAA58660 XM_005274194 XP_005274251 XM_011545218 XP_011543520 NM_003146 NP_003137
Function Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional co
Subcellular Location Nucleus. Nucleus, nucleolus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.

SSRP1 Antibody - 12009 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using SSRP1 Antibody.

SSRP1 (E1Y8D) Rabbit mAb - 13421 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1Y8D
Western blot analysis of extracts from various cell lines using SSRP1 (E1Y8D) Rabbit mAb.

SSRP1 (D-7) - sc-74536 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SSRP1 (D-7): sc-74536. Western blot analysis of SSRP1 expression in NIH/3T3 nuclear extract.

SSRP1 (D-15) - sc-5909 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SSRP1 (D-15): sc-5909. Western blot analysis of SSRP1 expression in non-transfected 293T: sc-117752 (A), mouse SSRP1 transfected 293T: sc-127593 (B) and HeLa (C) whole cell lysates.

SSRP1 (H-300) - sc-25382 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SSRP1 (H-300): sc-25382. Western blot analysis of SSRP1 expression in HeLa (A), UV-treated HeLa (B), K-562 (C) and HEL 92.1.7 (D) nuclear extracts.

SSRP1 (C-18) - sc-5911 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SSRP1 (C-18): sc-5911. Western blot analysis of SSRP1 expression in non-transfected: sc-117752 (A) and human SSRP1 transfected: sc-171570 (B) 293T whole cell lysates and K-562 nuclear extract (C).

SSRP1 (10D7) - sc-56781 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SSRP1 (10D7): sc-56781. Western blot analysis of SSRP1 expression in 293T whole cell lysate.

SSRP1 (3E4) - sc-56782 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SSRP1 (3E4): sc-56782. Western blot analysis of SSRP1 expression in 293T whole cell lysate.

Anti-SSRP1 antibody [10D7] - ab26212 from Abcam

Prices $394.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10D7
Anti-SSRP1 antibody [10D7] (ab26212) at 1 µg/ml + HeLa cell lysateSecondaryGoat anti-mouse Ig conjugated to HRP.developed using the ECL technique

Anti-SSRP1 antibody [3E4] - ab26229 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E4
Anti-SSRP1 antibody [3E4] (ab26229) at 1 µg/ml + HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate (ab7898)developed using the ECL technique

Anti-SSRP1 antibody [EPR7894] - ab129109 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7894
All lanes : Anti-SSRP1 antibody [EPR7894] (ab129109) at 1/10000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : MOLT4 cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-SSRP1 antibody [EPR7895] - ab137034 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7895
All lanes : Anti-SSRP1 antibody [EPR7895] (ab137034) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : 293T cell lysateLane 4 : MOLT4 cell lysateLane 5 : C6 cell lysateLane 6 : RAW 264.7 cell lysateLane 7 : PC12 cell lysateLane 8 : NIH 3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP conjugated Goat anti Rabbit IgG at 1/2000 dilution

Anti-FACT / SSRP1 Antibody (clone 3E4) - LS-C41041 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E4
Hela cell lysate was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal anti-SSRP1 antibody (clone 3E4). Proteins were detected using a goat anti-mouse Ig secondary conjugated to HRP and a chemiluminescence detection sy

Anti-FACT / SSRP1 Antibody (clone 1D4B) - LS-C189755 from LifeSpan Bioscience

Prices $325.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-FACT / SSRP1 Antibody (clone 1D4B) - LS-C189756 from LifeSpan Bioscience

Prices $325.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-FACT / SSRP1 Antibody (aa503-552) - LS-C109577 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SSRP1 antibody LS-C109577 Western blot of OVCAR-3 cell lysate.

Anti-FACT / SSRP1 Antibody (aa490-518, AP) - LS-C270430 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FACT / SSRP1 Antibody (N-Terminus) - LS-C80192 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-FACT / SSRP1 Antibody (aa611-660) - LS-C112354 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SSRP1 antibody LS-C112354 Western blot of Fetal Spleen lysate.

Anti-FACT / SSRP1 Antibody (aa490-518, APC) - LS-C270431 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FACT / SSRP1 Antibody (aa490-518, Biotin) - LS-C270432 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FACT / SSRP1 Antibody (aa490-518, FITC) - LS-C270433 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FACT / SSRP1 Antibody (clone 10D7) - LS-C41132 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10D7
Hela cell lysate was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal anti-SSRP1 antibody. Proteins were detected using a goat anti-mouse Ig secondary conjugated to HRP and a chemiluminescence detection system.

Anti-FACT / SSRP1 Antibody (aa490-518, PE) - LS-C270435 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FACT / SSRP1 Antibody (Internal, clone EPR7894) - LS-C152506 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7894
Western blot analysis on (A) K562, (B) HeLa, (C) Molt-4, and (D) 293T cell lysates using anti-SSRP1 antibody.
Search more