SSRP1

Gene Symbol	SSRP1
Entrez Gene	6749
Alt Symbol	FACT, FACT80, T160
Species	Human
Gene Type	protein-coding
Description	structure specific recognition protein 1
Other Description	FACT 80 kDa subunit|FACT complex subunit SSRP1|FACTp80|chromatin-specific transcription elongation factor 80 kDa subunit|cisplatin-DNA SSRP|facilitates chromatin remodeling 80 kDa subunit|facilitates chromatin transcription complex 80 kDa subunit|facilitates chromatin transcription complex subunit SSRP1|hSSRP1|high mobility group box|recombination signal sequence recognition protein 1|structure-specific recognition protein 1
Swissprots	Q5BJG8 Q08945
Accessions	CCQ43203 EAW73734 EAW73735 Q08945 AB209132 BAD92369 BC005116 AAH05116 BC091486 AAH91486 DQ893659 ABM84585 DQ895832 ABM86758 M86737 AAA58660 XM_005274194 XP_005274251 XM_011545218 XP_011543520 NM_003146 NP_003137
Function	Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional co
Subcellular Location	Nucleus. Nucleus, nucleolus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SSRP1 full length protein - ab132236 from Abcam Category Protein Source Wheat germ Species Human

Human SSRP1 peptide - ab22404 from Abcam Category Peptide

FACT / SSRP1 Antibody Blocking Peptide - LS-E3628 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FACT / SSRP1 Antibody Blocking Peptide - LS-E10844 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FACT / SSRP1 Antibody Blocking Peptide - LS-E10845 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FACT / SSRP1 Antibody Blocking Peptide - LS-E13738 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SSRP1 Protein - H00006749-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SSRP1 Protein - H00006749-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SSRP1-Antibody-C-term-Blocking-Peptide - BP14831b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SUPT16H blocking peptide - GTX89051-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Pig, Bovine

SSRP1 / FACT80 - H00006749-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SSRP1 / FACT80 - H00006749-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SSRP1 / FACT80 - H00006749-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SSRP1 / FACT80 - H00006749-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SSRP1 fusion protein - ag7945 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SSRP1 fusion protein - ag8318 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant SSRP1 / FACT p80 protein - 31345 from ActiveMotif Category Protein Prices $395.00 Sizes 10 µg Source Baculovirus Species Human

Recombinant Human SSRP1, His-tagged - SSRP1-29276TH from Creative Biomart Category Protein Source E. coli

Recombinant Structure Specific Recognition Protein 1 (SSRP1) - RPA423Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Structure Specific Recognition Protein 1 (SSRP1) - RPA423Hu01 from Cloud-clone Category Protein Source E.coli Species Human

SSRP1 / FACT80 - TP300414 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant SSRP1 / FACT p80 protein , Sf9 cells , 10 ug - HM-PR10206 from Novatein Biosciences Category Protein Prices $435.50 Sizes 10 µg Source Sf9 cells

SSRP1 Recombinant Protein Antigen - NBP1-84754PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SSRP1 Antibody - SH-A15967 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

SSRP1 Peptide, Human - M34GP15210H from Creative Peptides Category Peptide Source Synthetic. Species Human

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