SSRP1

Gene Symbol SSRP1
Entrez Gene 6749
Alt Symbol FACT, FACT80, T160
Species Human
Gene Type protein-coding
Description structure specific recognition protein 1
Other Description FACT 80 kDa subunit|FACT complex subunit SSRP1|FACTp80|chromatin-specific transcription elongation factor 80 kDa subunit|cisplatin-DNA SSRP|facilitates chromatin remodeling 80 kDa subunit|facilitates chromatin transcription complex 80 kDa subunit|facilitates chromatin transcription complex subunit SSRP1|hSSRP1|high mobility group box|recombination signal sequence recognition protein 1|structure-specific recognition protein 1
Swissprots Q5BJG8 Q08945
Accessions CCQ43203 EAW73734 EAW73735 Q08945 AB209132 BAD92369 BC005116 AAH05116 BC091486 AAH91486 DQ893659 ABM84585 DQ895832 ABM86758 M86737 AAA58660 XM_005274194 XP_005274251 XM_011545218 XP_011543520 NM_003146 NP_003137
Function Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional co
Subcellular Location Nucleus. Nucleus, nucleolus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.

SSRP1 CRISPR/Cas9 KO Plasmid (h) - sc-401780 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 HDR Plasmid (h) - sc-401780-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 Double Nickase Plasmid (h) - sc-401780-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 Double Nickase Plasmid (h2) - sc-401780-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 CRISPR Activation Plasmid (h) - sc-401780-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 CRISPR Activation Plasmid (h2) - sc-401780-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 Lentiviral Activation Particles (h) - sc-401780-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 Lentiviral Activation Particles (h2) - sc-401780-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 siRNA (h) - sc-37877 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SSRP1 shRNA Plasmid (h) - sc-37877-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SSRP1 shRNA (h) Lentiviral Particles - sc-37877-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SSRP1 RNAi - H00006749-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015991 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20631 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20631 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03118 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03118

SSRP1 siRNA (Human) - CRH4612 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SSRP1 - MBS8222933 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SSRP1 CRISPR/Cas9 KO Plasmid (h2) - sc-401780-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SSRP1 HDR Plasmid (h2) - sc-401780-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human SSRP1 (NM_003146.2) - SHH418532 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SSRP1(NM_003146.2) - SHL036430 from Creative biogene

Category siRNA
Species Reactivities Human

Human SSRP1 siRNA - orb265114 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SSRP1 shRNA Plasmid (Human) - CHH4612 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SSRP1 miRNA 3'UTR clone - MiUTR1H-09928 from Creative biogene

Species Reactivities Human
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