MAGEA3

Gene Symbol	MAGEA3
Entrez Gene	4102
Alt Symbol	CT1.3, HIP8, HYPD, MAGE3, MAGEA6
Species	Human
Gene Type	protein-coding
Description	melanoma antigen family A3
Other Description	MAGE-3 antigen|antigen MZ2-D|cancer/testis antigen 1.3|cancer/testis antigen family 1, member 3|melanoma antigen family A, 3|melanoma-associated antigen 3
Swissprots	Q6FHI6 P43357
Accessions	AAA17446 P43357 AK223519 BAD97239 AK292384 BAF85073 BC000340 AAH00340 BC005963 AAH05963 BC011744 AAH11744 BC016803 AAH16803 BC017389 AAH17389 CR541767 CAG46566 CR541768 CAG46567 CR541774 CAG46573 CR542020 CAG46817 DQ891850 ABM82776 DQ895040 ABM85966 XM_005274676 XP_005274733 XM_006724818 XP_006724881 XM_011531160 XP_011529462 XM_011531161 XP_011529463 NM_005362 NP_005353
Function	Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. {ECO:0000269|PubMed:20864041}.
Tissue Specificity	Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Never expressed in kidney tumors, Leukemias and lymphomas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAGEA3 full length protein - ab99958 from Abcam Category Protein Source E. coli Species Human

MAGEA3 Antibody Blocking Peptide - LS-E8105 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAGEA3 Antibody Blocking Peptide - LS-E16818 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAGEA6 Antibody Blocking Peptide - LS-E8107 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAGEA6 Antibody Blocking Peptide - LS-E16819 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAGEA3 Partial Recombinant Protein - H00004102-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MAGEA6 Recombinant Protein - H00004105-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MAGEA3 Protein - NBP1-49445 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

MAGEA3 Recombinant Protein - H00004102-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

Recombinant Human MAGEA6 Protein - NBP1-98966 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

MAGEA6 Peptide - P1776 from Novus Biologicals Category Peptide Species Human

MAGEA3 Peptide - P1773 from Novus Biologicals Category Peptide Species Human

MAGEA3-Antibody-C-term-Blocking-Peptide - BP6165a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAGE-3-271-279 - SP2224b from Abgent, a WuXi AppTec company Category Peptide Prices $155.00 Sizes 5 mg

MAGE-3-271-279 - SP2224a from Abgent, a WuXi AppTec company Category Peptide Prices $100.00 Sizes 1 mg

MAGE-3-114-127 - SP2141b from Abgent, a WuXi AppTec company Category Peptide Prices $170.00 Sizes 5 mg

MAGE-3-114-127 - SP2141a from Abgent, a WuXi AppTec company Category Peptide Prices $100.00 Sizes 1 mg

MAGE-A3-167-176 - SP2334b from Abgent, a WuXi AppTec company Category Peptide Prices $170.00 Sizes 5 mg

MAGE-A3-167-176 - SP2334a from Abgent, a WuXi AppTec company Category Peptide Prices $125.00 Sizes 1 mg

MAGE-3-121-134 - SP2323b from Abgent, a WuXi AppTec company Category Peptide Prices $170.00 Sizes 5 mg

MAGE-3-121-134 - SP2323a from Abgent, a WuXi AppTec company Category Peptide Prices $100.00 Sizes 1 mg

MAGEA3 protein (His tag) - GTX14671 from GeneTex Category Protein Prices $429.00 Sizes 50 μg

Human MAGEA6 protein - orb168766 from Biorbyt Category Protein Prices $230.00, $442.00, $1,811.00 Sizes 2 μg, 10 μg, 100 μg Source E.coli Species Human

MAGEA3 Blocking Peptide - 33R-1420 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MAGEA3 protein (His tag) - 80R-1519 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

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