Plg

Gene Symbol	Plg
Entrez Gene	18815
Alt Symbol	AI649309, Pg
Species	Mouse
Gene Type	protein-coding
Description	plasminogen
Other Description	angiostatin|plasmin heavy chain A|plasmin light chain B
Swissprots	Q8CIS2 Q91WJ5 P20918
Accessions	AAM22156 AAN15805 EDL02061 EDL02062 EDL02063 EDL02064 EDL02065 EDL02066 EDL02067 EDL02068 EDL02069 EDL02070 EDL02071 EDL02072 P20918 AK040840 AK132254 BAE21060 AY424276 AAR07361 BC014773 AAH14773 BC057186 AAH57186 BY131661 J04766 AAA50168 NM_008877 NP_032903
Function	Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity). {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000250}. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity). {ECO:0000250}.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Plasminogen Total (PLG) Mouse ELISA Kit - ab198511 from Abcam Category ELISA Kit Prices $475.00 Sizes 1 x 96 tests Sensitivity 0.49 ng/ml Range 1 ng/ml - 500 ng/ml

Mouse Angiostatin ELISA Kit (Sandwich ELISA) - LS-F6507 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 31.25-1000 ng/ml

Angiostatin, Mouse, ELISA Kit - E03A0687 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/mL Range 25-500ng/mL

Plasminogen (PLG), Mouse, ELISA Kit - CSB-EL018188MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Plasminogen, Mouse, ELISA Kit - E03P0127 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Range 25-500ng/ml

Plasminogen, Plg, Mouse, ELISA Kit - E1236m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Plg (Mouse) ELISA Kit - KA1845 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Plg (Mouse) ELISA Kit - KA1846 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Mouse Plg ELISA Kit - MP0134 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

plasminogen total antigen assay - MBS135494 from MyBioSource Category ELISA Kit

Mouse Plasminogen ELISA Kit - GWB-13E28E from Genway Biotech Category ELISA Kit Prices $473.00 Sizes 96 well Sensitivity 0.858 ng/ml Range Refer To Manual

Mouse Plasminogen ELISA Kit - DEIA8401 from Creative Diagnostics Category ELISA Kit

Angiostatin (ANG), ELISA Kit - MBS2019712 from MyBioSource Category ELISA Kit Prices $370.00, $550.00, $750.00, $3,065.00, $5,550.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of angiostatin is typically less than 0.127ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL. The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.312ng/mL.

plasminogen, ELISA Kit - MBS910701 from MyBioSource Category ELISA Kit Prices $250.00, $860.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse PLG is typically less than 15.63 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 62.5 ng/ml -4000 ng/ml.

Mouse Plasminogen(PLG) ELISA kit - CSB-EL018188MO from Cusabio Category ELISA Kit Sensitivity 15.63 ng/ml Range 62.5 ng/ml-4000 ng/ml

Mouse Plasminogen ELISA - E03P0127 from BlueGene Biotech Category ELISA Kit Sensitivity 1.0ng/mL

Mouse Plasminogen (PLG) ELISA Kit - EMP2211-1 from AssayPro Category ELISA Kit Range 0.5-8 ug/ml

Mouse Plasminogen (PLG) ELISA Kit - EMP1200-1 from AssayPro Category ELISA Kit Range 0.188-12 ng/ml

Plasminogen - KSP-527 from Nordic BioSite Range 0.5-8 ug/ml

Plasminogen - KSP-528 from Nordic BioSite Range 0.188-12 ng/ml

Mouse Angiostatin (ANG) ELISA Kit - EKU02383 from Biomatik Category ELISA Kit Prices $718.00, $3,196.00, $5,817.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.127 ng/mL Range 0.312-20 ng/mL

Plasminogen ELISA kit - ARG80937 from Arigo Biolaboratories Category ELISA Kit Range 2.5-500 ng/ml

Mouse Angiostatin ELISA Kit - abx153635 from Abbexa Category ELISA Kit Range 0.313 ng/ml - 20 ng/ml

Mouse PLG ELISA Kit - CSI19895A from Cell Science Category ELISA Kit Prices $595.00 Sizes 1 plate

Mouse PLG ELISA Kit - CSI19895B from Cell Science Category ELISA Kit Prices $2,450.00 Sizes 5 plates

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