Plg

Gene Symbol Plg
Entrez Gene 18815
Alt Symbol AI649309, Pg
Species Mouse
Gene Type protein-coding
Description plasminogen
Other Description angiostatin|plasmin heavy chain A|plasmin light chain B
Swissprots Q8CIS2 Q91WJ5 P20918
Accessions AAM22156 AAN15805 EDL02061 EDL02062 EDL02063 EDL02064 EDL02065 EDL02066 EDL02067 EDL02068 EDL02069 EDL02070 EDL02071 EDL02072 P20918 AK040840 AK132254 BAE21060 AY424276 AAR07361 BC014773 AAH14773 BC057186 AAH57186 BY131661 J04766 AAA50168 NM_008877 NP_032903
Function Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity). {ECO:0000250}.
Subcellular Location Secreted {ECO:0000250}. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity). {ECO:0000250}.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A, Neuroactive ligand-receptor interaction

Plasminogen CRISPR/Cas9 KO Plasmid (m) - sc-422307 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen HDR Plasmid (m) - sc-422307-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen Double Nickase Plasmid (m) - sc-422307-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen Double Nickase Plasmid (m2) - sc-422307-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen CRISPR Activation Plasmid (m) - sc-422307-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen CRISPR Activation Plasmid (m2) - sc-422307-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen Lentiviral Activation Particles (m) - sc-422307-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Plasminogen Lentiviral Activation Particles (m2) - sc-422307-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

plasminogen siRNA (m) - sc-40858 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

plasminogen shRNA Plasmid (m) - sc-40858-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

plasminogen shRNA (m) Lentiviral Particles - sc-40858-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU196041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN38905 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38905 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLG siRNA (Mouse) - CRM3126 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Plg (NM_008877.3) - SHH377808 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse PLG siRNA - orb282602 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

PLG shRNA Plasmid (Mouse) - CHM3126 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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