NUDT3

Gene Symbol	NUDT3
Entrez Gene	11165
Alt Symbol	DIPP, DIPP-1, DIPP1
Species	Human
Gene Type	protein-coding
Description	nudix (nucleoside diphosphate linked moiety X)-type motif 3
Other Description	diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1|diphosphoinositol polyphosphate phosphohydrolase 1|nucleoside diphosphate-linked moiety X motif 3|nudix motif 3
Swissprots	O95989 B2R8N4
Accessions	EAX03781 O95989 AF062529 AAC83224 AF062530 AAC83225 AK313440 BAG36231 BC007727 AAH07727 BC024593 BG714472 BT019984 AAV38787 BT019985 AAV38788 CA430332 DA803962 DQ893118 ABM84044 DQ896391 ABM87390 NM_006703 NP_006694
Function	Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5- phosphoribose 1-diphosphate. {ECO:0000269|PubMed:9822604}.
Subcellular Location	Cytoplasm {ECO:0000305}.
Tissue Specificity	Widely expressed. Expressed at higher level in brain, heart, pancreas and liver. Also expressed in placenta, lung and kidney. {ECO:0000269|PubMed:9822604}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NUDT3 full length protein - ab103915 from Abcam Category Protein Source E. coli Species Human

NUDT3 Antibody Blocking Peptide - LS-E24587 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUDT3 Recombinant Protein - H00011165-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NUDT3 Protein - NBP1-50999 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 50 µg, 250 µg Source E.coli Species Human

Human NUDT3 protein - orb168959 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

NUDT3 protein (His tag) - 80R-1680 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

NUDT3 / DIPP1 (1-172, His-tag) - AR09862PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

NUDT3 / DIPP1 (1-172, His-tag) - AR09862PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

NUDT3 / DIPP1 - H00011165-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NUDT3 / DIPP1 - H00011165-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Nudix Type Motif 3, Human Recombinant - 228-12223-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

NUDT3, 1-172aa, Human, His tag, E.coli - 01-1884-3 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

NUDT3 fusion protein - Ag14587 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NUDT3 fusion protein - Ag15163 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NUDT3 Human - ENPS-078 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human NUDT3 - BP000686-ENZ-071 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

NUDT3, 1-172aa, Recombinant Protein - GWB-P1116K from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

NUDT3 Human Protein - GWB-BSP263 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human NUDT3, His-tagged - NUDT3-3476H from Creative Biomart Category Protein

Recombinant Human NUDT3, His-tagged - NUDT3-27534TH from Creative Biomart Category Protein Source E. coli

Recombinant Human NUDT3, GST-tagged - NUDT3-1406H from Creative Biomart Category Protein Source E.coli Species Human

NUDT3 1-172aa - CMB-755 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

NUDT3 - JNV-015 from Reagent Proteins Category Protein Prices $364.00, $5,334.00 Sizes 10.00 µg, 1 mg Source E.coli

Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 1(NUDT3) - CSB-YP530966HU CSB-EP530966HU CSB-BP530966HU CSB-MP530966HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NuDT3, 1-172aa, Human, His tag, E.coli - ATGP0922 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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