NUDT3

Gene Symbol NUDT3
Entrez Gene 11165
Alt Symbol DIPP, DIPP-1, DIPP1
Species Human
Gene Type protein-coding
Description nudix (nucleoside diphosphate linked moiety X)-type motif 3
Other Description diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1|diphosphoinositol polyphosphate phosphohydrolase 1|nucleoside diphosphate-linked moiety X motif 3|nudix motif 3
Swissprots O95989 B2R8N4
Accessions EAX03781 O95989 AF062529 AAC83224 AF062530 AAC83225 AK313440 BAG36231 BC007727 AAH07727 BC024593 BG714472 BT019984 AAV38787 BT019985 AAV38788 CA430332 DA803962 DQ893118 ABM84044 DQ896391 ABM87390 NM_006703 NP_006694
Function Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5- phosphoribose 1-diphosphate. {ECO:0000269|PubMed:9822604}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Widely expressed. Expressed at higher level in brain, heart, pancreas and liver. Also expressed in placenta, lung and kidney. {ECO:0000269|PubMed:9822604}.

NUDT3 CRISPR/Cas9 KO Plasmid (h) - sc-406785 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 HDR Plasmid (h) - sc-406785-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 Double Nickase Plasmid (h) - sc-406785-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 Double Nickase Plasmid (h2) - sc-406785-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 CRISPR Activation Plasmid (h) - sc-406785-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 CRISPR Activation Plasmid (h2) - sc-406785-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 Lentiviral Activation Particles (h) - sc-406785-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 Lentiviral Activation Particles (h2) - sc-406785-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT3 siRNA (h) - sc-95560 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NUDT3 shRNA Plasmid (h) - sc-95560-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NUDT3 shRNA (h) Lentiviral Particles - sc-95560-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NUDT3 RNAi - H00011165-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15602 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15602 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04959 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04959

NUDT3 siRNA (Human) - CRH7646 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NUDT3 (NM_006703.3) - SHH356184 from Creative biogene

Category siRNA
Species Reactivities Human

NUDT3 shRNA Plasmid (Human) - CHH7646 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NUDT3 miRNA 3'UTR clone - MiUTR3H-10494 from Creative biogene

Species Reactivities Human
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