RXFP2

Gene Symbol RXFP2
Entrez Gene 122042
Alt Symbol GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2
Species Human
Gene Type protein-coding
Description relaxin/insulin-like family peptide receptor 2
Other Description G protein coupled receptor affecting testicular descent|G-protein coupled receptor 106|G-protein coupled receptor affecting testicular descent|leucine-rich repeat-containing G protein-coupled receptor 8|leucine-rich repeat-containing G-protein coupled receptor 8|relaxin family peptide receptor 2|relaxin receptor 2
Swissprots Q3KU23 B1ALE9 Q8WXD0
Accessions EAX08484 EAX08485 Q8WXD0 AF403384 AAL69324 AF453828 AAL73946 AY899851 AAX85199 BC146279 AAI46280 BC148729 AAI48730 XM_011534918 XP_011533220 NM_001166058 NP_001159530 NM_130806 NP_570718
Function Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.
Top Pathways Neuroactive ligand-receptor interaction

Relaxin Receptor 2 (H-4) - sc-374293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Relaxin Receptor 2 (H-4): sc-374293. Western blot analysis of Relaxin Receptor 2 expression in Jurkat (A) and HeLa (B) whole cell lysates.

Relaxin Receptor 2 (G-14) - sc-32850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Relaxin Receptor 2 (H-150) - sc-50327 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Relaxin Receptor 2 (C-18) - sc-26131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Relaxin Receptor 2 (C-18): sc-26131. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Relaxin Receptor 2 (L-20) - sc-22015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Relaxin Receptor 2 (L-20): sc-22015. Western blot analysis of Relaxin Receptor 2 expression in IMR-32 (A), HeLa (B), HUV-EC-C (C), Ramos (D) and K-562 (E) whole cell lysates.

Relaxin Receptor 2 (S-13) - sc-32849 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GPCR LGR8 antibody - ab95449 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GPCR LGR8 antibody - ab138011 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GPCR LGR8 antibody (ab138011) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-RXFP2 / LGR8 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A4753 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RXFP2 / LGR8 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-RXFP2 / LGR8 Antibody (Internal) - LS-C145116 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa737-754) - LS-C190994 from LifeSpan Bioscience

Prices $800.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa653-702) - LS-C151147 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RXFP2 / LGR8 antibody Western Blot of Jurkat.

Anti-RXFP2 / LGR8 Antibody (aa692-721, AP) - LS-C217366 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa692-721, APC) - LS-C217367 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa103-152) - LS-C200634 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HUVEC cells using RXFP2 antibody.

Anti-RXFP2 / LGR8 Antibody (aa692-721, Biotin) - LS-C217368 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa113-162) - LS-C120948 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using RXFP2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-RXFP2 / LGR8 Antibody (aa692-721, FITC) - LS-C217369 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa692-721, Azide-free, HRP) - LS-C217371 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (Leu152) - LS-C177304 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Relaxin Receptor 2 (L152) pAb in extracts from Jurkat cells.

Anti-RXFP2 / LGR8 Antibody (aa692-721, PE) - LS-C217372 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa692-721) - LS-C324872 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP2 / LGR8 Antibody (aa692-721) - LS-C158910 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RXFP2 Antibody western blot of Ramos cell line lysates (35 ug/lane). The RXFP2 antibody detected the RXFP2 protein (arrow).

Anti-RXFP2 / LGR8 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A4754 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RXFP2 antibody LS-A4754 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-RXFP2 / LGR8 Antibody (C-Terminus) IHC-plus™ - LS-A4752 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RXFP2 antibody LS-A4752 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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