Gene Symbol | RXFP2 |
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Entrez Gene | 122042 |
Alt Symbol | GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2 |
Species | Human |
Gene Type | protein-coding |
Description | relaxin/insulin-like family peptide receptor 2 |
Other Description | G protein coupled receptor affecting testicular descent|G-protein coupled receptor 106|G-protein coupled receptor affecting testicular descent|leucine-rich repeat-containing G protein-coupled receptor 8|leucine-rich repeat-containing G-protein coupled receptor 8|relaxin family peptide receptor 2|relaxin receptor 2 |
Swissprots | Q3KU23 B1ALE9 Q8WXD0 |
Accessions | EAX08484 EAX08485 Q8WXD0 AF403384 AAL69324 AF453828 AAL73946 AY899851 AAX85199 BC146279 AAI46280 BC148729 AAI48730 XM_011534918 XP_011533220 NM_001166058 NP_001159530 NM_130806 NP_570718 |
Function | Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow. |
Top Pathways | Neuroactive ligand-receptor interaction |
RXFP2 / LGR8 Antibody Blocking Peptide - LS-E6302 from LifeSpan Bioscience
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RXFP2 / LGR8 Antibody Blocking Peptide - LS-E28987 from LifeSpan Bioscience
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RXFP2 / LGR8 Antibody Blocking Peptide - LS-E28988 from LifeSpan Bioscience
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RXFP2 / LGR8 Antibody Blocking Peptide - LS-E28989 from LifeSpan Bioscience
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RXFP2 / LGR8 Antibody Blocking Peptide - LS-E28990 from LifeSpan Bioscience
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RXFP2 / LGR8 Antibody Blocking Peptide - LS-E23278 from LifeSpan Bioscience
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Recombinant Human Relaxin R2/LGR8 Protein - H00122042-G01 from Novus Biologicals
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RXFP2-Antibody-C-term-Blocking-Peptide - BP18991b from Abgent, a WuXi AppTec company
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Relaxin receptor 2 / RXFP2 - H00122042-G01 from Acris Antibodies
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RXFP2 fusion protein - ag18620 from Proteintech Group
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RXFP2 fusion protein - ag18834 from Proteintech Group
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Relaxin Receptor 2 (L152) Peptide - BS2959P from Bioworld Technology
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RXFP2 Peptide, Human - M34GP13707H from Creative Peptides
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Relaxin receptor 2 (RXFP2), Recombinant Protein - MBS7029193 from MyBioSource
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