IPO7

Gene Symbol	IPO7
Entrez Gene	10527
Alt Symbol	Imp7, RANBP7
Species	Human
Gene Type	protein-coding
Description	importin 7
Other Description	RAN-binding protein 7|importin-7
Swissprots	A6NNM5 Q9NTE3 Q9H177 Q1RMF7 O95373 B2R786
Accessions	CAC17609 EAW68591 EAW68592 EAW68593 O95373 AF098799 AAC68903 AK027487 BAG51331 AK027892 BAG51391 AK074908 BAG52028 AK312885 BAG35733 AL117596 AL137335 CAB70698 BC114929 AAI14930 BM980653 BX342418 DA780921 NM_006391 NP_006382
Function	Functions in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In association with KPNB1 mediates the nuclear import of H1 h
Subcellular Location	Cytoplasm. Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Importin 7 peptide - ab23277 from Abcam Category Peptide Species Human

Human Importin 7 protein fragment - ab153096 from Abcam Category Protein Source Wheat germ Species Human

IPO7 / RANBP7 Antibody Blocking Peptide - LS-E23660 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IPO7 / RANBP7 Antibody Blocking Peptide - LS-E25401 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Importin-7 Protein - H00010527-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Importin 7 blocking peptide - GTX15840-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

IPO7 Immunizing peptide - orb17695 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Importin 7 Peptide - AC21-0229-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

RanBP7 / Importin-7 - H00010527-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RanBP7 / Importin-7 - H00010527-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Importin 7 Peptide - 45-770P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human Importin-7(IPO7) ,partial - CSB-YP011779HU CSB-EP011779HU CSB-BP011779HU CSB-MP011779HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RANBP7/Importin 7, Peptide - MBS426840 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

Importin-7 Recombinant Protein Antigen - NBP1-87880PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IPO7-Blocking-Peptide-N-term - BP5434a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IPO7 Peptide, Human - M34GP07705H from Creative Peptides Category Peptide Source Synthetic. Species Human

Importin-7 Recombinant Protein Antigen - NBP2-56778PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Importin-7 (IPO7), partial, Recombinant Protein - MBS1050926 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

IPO7 fusion protein - Ag27257 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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