Gene Symbol | EREG |
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Entrez Gene | 2069 |
Alt Symbol | ER |
Species | Human |
Gene Type | protein-coding |
Description | epiregulin |
Other Description | proepiregulin |
Swissprots | O14944 Q6FH69 B2RC66 |
Accessions | EAX05709 O14944 AK314959 BAG37463 BC035806 BC136404 AAI36405 BC136405 AAI36406 CR541887 CAG46685 D30783 BAA22146 NM_001432 NP_001423 |
Function | Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. {ECO:0000269|PubMed:9419975}. |
Subcellular Location | Epiregulin: Secreted, extracellular space. |
Tissue Specificity | In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. |
Top Pathways | ErbB signaling pathway |
EREG (D4O5I) Rabbit mAb - 12048 from Cell Signaling Technology
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Epiregulin (C-15) - sc-25231 from Santa Cruz Biotechnology
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Epiregulin (FL-162) - sc-30215 from Santa Cruz Biotechnology
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Anti-EREG antibody - ab168783 from Abcam
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Anti-EREG antibody - ab195620 from Abcam
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Anti-EREG antibody [MM0265- 12Y4] - ab89291 from Abcam
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Anti-EREG antibody - C-terminal - ab175118 from Abcam
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Anti-ER-MP58 Antibody (clone ER-MP58) - LS-C188296 from LifeSpan Bioscience
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Anti-ER-TR7 Antibody (clone ER-TR7) - LS-C188302 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa137-165, AP) - LS-C256776 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa137-165, Biotin) - LS-C256778 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa137-165, APC) - LS-C256777 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa137-165, Azide-free, HRP) - LS-C256780 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa30-169, Biotin) - LS-C298117 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody - LS-C307424 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa30-169, FITC) - LS-C302638 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa140-169) - LS-C321167 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (Internal) - LS-C136977 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa1-162) - LS-C314859 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (clone 1E6) - LS-C197154 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa30-169) - LS-C294136 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa137-165, FITC) - LS-C256779 from LifeSpan Bioscience
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Anti-EREG / Epiregulin Antibody (aa137-165) - LS-C167801 from LifeSpan Bioscience
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Epiregulin Antibody [Unconjugated] - AF1195 from Novus Biologicals
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Epiregulin Antibody - NBP2-31577 from Novus Biologicals
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