PRG4

Gene Symbol	PRG4
Entrez Gene	10216
Alt Symbol	CACP, HAPO, JCAP, MSF, SZP
Species	Human
Gene Type	protein-coding
Description	proteoglycan 4
Other Description	articular superficial zone protein|hemangiopoietin|lubricin|megakaryocyte stimulating factor|superficial zone proteoglycan
Swissprots	Q9BX49 Q6DNC5 Q92954 Q6ZMZ5 Q6DNC4
Accessions	EAW91201 EAW91202 Q92954 AK057197 BAG51882 AK131434 BAD18580 AK297718 BAH12654 AK301343 BAG62891 AK301487 BAH13495 AK308235 AY653037 AAT74745 AY653038 AAT74746 CA435357 DA977744 DA995681 DC295855 DC404857 U70136 AAB09089 NM_001127708 NP_001121180 NM_001127709 NP_001121181 NM_001127710 NP_001121182 NM_001303232 NP_001290161 NM_005807 NP_005798
Function	Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.
Subcellular Location	Secreted {ECO:0000269|PubMed:14976050}.
Tissue Specificity	Highly expressed in synovial tissue, cartilage and liver and weakly in heart and lung. Isoform B is expressed in kidney, lung, liver, heart and brain. Isoform C and isoform D are widely expressed. {ECO:0000269|PubMed:10545950, ECO:0000269|PubMed:11124536}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Lubricin (E-19) - sc-50079 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Lubricin (P-19) - sc-50081 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Lubricin (C-17) - sc-50078 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Lubricin (N-16) - sc-50080 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Lubricin (H-140) - sc-98454 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Lubricin antibody - ab195590 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Lubricin antibody - ab94933 from Abcam Prices $370.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody (C-Terminus) - LS-C144887 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody (Internal) - LS-C87260 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody (aa1151-1241, Biotin) - LS-C298503 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody (aa1151-1241, FITC) - LS-C305156 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody (aa1151-1241) - LS-C296142 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody (clone 1D5) - LS-C139223 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1D5

Anti-Proteoglycan 4 / Lubricin Antibody (C-Terminus) IHC-plus™ - LS-B8236 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-Proteoglycan 4 / Lubricin Antibody - LS-C137213 from LifeSpan Bioscience Prices $255.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Proteoglycan 4 Antibody - NBP1-19048 from Novus Biologicals Prices $299.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Proteoglycan 4 Antibody (2A6) - H00010216-M01 from Novus Biologicals Prices $349.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2A6

Proteoglycan 4 Antibody - NB100-74453 from Novus Biologicals Prices $299.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Proteoglycan 4 Antibody - NBP1-89984 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Proteoglycan 4 Antibody (1D5) - H00010216-M02 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1D5

Proteoglycan 4 Antibody - NBP1-20940 from Novus Biologicals Prices $199.00 Sizes 100 µg Host Goat Clonality Polyclonal

Proteoglycan 4 Antibody (2A6) - H00010216-M01A from Novus Biologicals Prices $349.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 2A6

Monoclonal Anti-PRG4, (C-terminal) antibody produced in mouse - SAB1404799 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1D5

Anti-PRG4 antibody produced in rabbit - HPA028523 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Monoclonal Anti-PRG4 antibody produced in mouse - WH0010216M1 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2A6

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