PRG4

Gene Symbol PRG4
Entrez Gene 10216
Alt Symbol CACP, HAPO, JCAP, MSF, SZP
Species Human
Gene Type protein-coding
Description proteoglycan 4
Other Description articular superficial zone protein|hemangiopoietin|lubricin|megakaryocyte stimulating factor|superficial zone proteoglycan
Swissprots Q9BX49 Q6DNC5 Q92954 Q6ZMZ5 Q6DNC4
Accessions EAW91201 EAW91202 Q92954 AK057197 BAG51882 AK131434 BAD18580 AK297718 BAH12654 AK301343 BAG62891 AK301487 BAH13495 AK308235 AY653037 AAT74745 AY653038 AAT74746 CA435357 DA977744 DA995681 DC295855 DC404857 U70136 AAB09089 NM_001127708 NP_001121180 NM_001127709 NP_001121181 NM_001127710 NP_001121182 NM_001303232 NP_001290161 NM_005807 NP_005798
Function Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.
Subcellular Location Secreted {ECO:0000269|PubMed:14976050}.
Tissue Specificity Highly expressed in synovial tissue, cartilage and liver and weakly in heart and lung. Isoform B is expressed in kidney, lung, liver, heart and brain. Isoform C and isoform D are widely expressed. {ECO:0000269|PubMed:10545950, ECO:0000269|PubMed:11124536}.

Lubricin CRISPR/Cas9 KO Plasmid (h) - sc-402340 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin HDR Plasmid (h) - sc-402340-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin Double Nickase Plasmid (h) - sc-402340-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin Double Nickase Plasmid (h2) - sc-402340-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin CRISPR Activation Plasmid (h) - sc-402340-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin CRISPR Activation Plasmid (h2) - sc-402340-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin Lentiviral Activation Particles (h) - sc-402340-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin Lentiviral Activation Particles (h2) - sc-402340-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lubricin siRNA (h) - sc-60972 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Lubricin shRNA Plasmid (h) - sc-60972-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Lubricin shRNA (h) Lentiviral Particles - sc-60972-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Proteoglycan 4 RNAi - H00010216-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17398 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17398 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06434 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06434

PRG4 siRNA (Human) - CRH6905 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRG4 (NM_005807.3) - SHH382504 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRG4 siRNA - orb267407 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRG4 shRNA Plasmid (Human) - CHH6905 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRG4 miRNA 3'UTR clone - MiUTR3H-06694 from Creative biogene

Species Reactivities Human

PRG4 miRNA 3'UTR clone - MiUTR3H-06695 from Creative biogene

Species Reactivities Human

PRG4 miRNA 3'UTR clone - MiUTR3H-06696 from Creative biogene

Species Reactivities Human

PRG4 miRNA 3'UTR clone - MiUTR3H-06697 from Creative biogene

Species Reactivities Human
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