LIN7C

Gene Symbol	LIN7C
Entrez Gene	55327
Alt Symbol	LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3
Species	Human
Gene Type	protein-coding
Description	lin-7 homolog C (C. elegans)
Other Description	LIN-7 protein 3|mammalian lin-seven protein 3|protein lin-7 homolog C|veli-3|vertebrate lin-7 homolog 3
Swissprots	Q9NUP9
Accessions	EAW68282 EAW68283 Q9NUP9 AF090900 AAF24024 AK002077 BAA92072 AK025540 AK223156 BAD96876 AL833601 BC009774 BC039459 BC053907 AAH53907 DA231006 NM_018362 NP_060832
Function	Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000269|PubMed:12967566}. Basolateral cell membrane {ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000269|PubMed:12967566}. Cell junction {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Enriched in synaptosomes and at epithelial cell-cell junctions (By similarity). Mainly basolateral in renal epithelial cells. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LIN7C full length protein - ab137173 from Abcam Category Protein Source E. coli Species Human

LIN7C / VELI3 Antibody Blocking Peptide - LS-E1954 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIN7C / VELI3 Antibody Blocking Peptide - LS-E15788 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIN7C / VELI3 Antibody Blocking Peptide - LS-E15787 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIN7C Recombinant Protein - H00055327-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human LIN7C Protein - NBP2-23199 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

LIN7C-Antibody-C-term-Blocking-peptide - BP12807b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human LIN7C protein - orb168740 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

LIN7C Blocking Peptide - 33R-5599 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LIN7C Blocking Peptide - 33R-6031 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LIN7C protein (His tag) - 80R-2615 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

LIN7C (1-197, His-tag) - AR50661PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

LIN7C (1-197, His-tag) - AR50661PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

LIN7C - H00055327-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

LIN7C - H00055327-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

LIN7C, 1-197 aa, Human, His tag, E.coli - 01-P1837 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

LIN7C fusion protein - Ag6265 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human lin-7 homolog C (C. elegans), His-tagged - LIN7C-398H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein lin-7 homolog C(LIN7C) - CSB-YP873657HU CSB-EP873657HU CSB-BP873657HU CSB-MP873657HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LIN7C, 1-197aa, Human, His tag, E.coli - ATGP1837 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

LIN7C Protein (Recombinant) - abx260989 from Abbexa Category Protein

LIN7C - TP308758 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

LIN7C Recombinant Protein Antigen - NBP2-14193PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

LIN7C Peptide, Human - M34GP08730H from Creative Peptides Category Peptide Source Synthetic. Species Human

LIN7C Antibody - SH-A13326 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

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