LIN7C

Gene Symbol LIN7C
Entrez Gene 55327
Alt Symbol LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3
Species Human
Gene Type protein-coding
Description lin-7 homolog C (C. elegans)
Other Description LIN-7 protein 3|mammalian lin-seven protein 3|protein lin-7 homolog C|veli-3|vertebrate lin-7 homolog 3
Swissprots Q9NUP9
Accessions EAW68282 EAW68283 Q9NUP9 AF090900 AAF24024 AK002077 BAA92072 AK025540 AK223156 BAD96876 AL833601 BC009774 BC039459 BC053907 AAH53907 DA231006 NM_018362 NP_060832
Function Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000269|PubMed:12967566}. Basolateral cell membrane {ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000269|PubMed:12967566}. Cell junction {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Enriched in synaptosomes and at epithelial cell-cell junctions (By similarity). Mainly basolateral in renal epithelial cells. {ECO:0000250}.

Veli3 (N-17) - sc-11504 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LIN7 antibody - ab127049 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-LIN7 antibody (ab127049) at 1/5000 dilution + MCF7 whole cell lysate at 30 µg

Anti-LIN7 antibody - ab104589 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-LIN7 antibody - ab11472 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C antibody - ab82646 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LIN7C antibody (ab82646) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-LIN7C antibody - C-terminal - ab170745 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labeling LIN7C with ab170745 at 1/10 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-LIN7C / VELI3 Antibody (C-Terminus) - LS-C40175 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197, APC) - LS-C237141 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197, AP) - LS-C237142 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197, Biotin) - LS-C237144 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197, FITC) - LS-C237143 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197, Azide-free, HRP) - LS-C248713 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197, PE) - LS-C237145 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa175-197) - LS-C322668 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN7C / VELI3 Antibody (aa168-197) - LS-C165785 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LIN7C Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-LIN7C / VELI3 Antibody (aa108-157) IHC-plus™ - LS-B11504 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-LIN7C / VELI3 Antibody (N-Terminus) IHC-plus™ - LS-B3550 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LIN7C antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3550 concentration 5 ug/ml.

LIN7C Antibody - NBP1-53082 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LIN7C Antibody [NBP1-53082] - HepG2 cell lysate, concentration 1 ug/ml.

LIN7C Antibody - NBP2-14193 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: LIN7C Antibody [NBP2-14193] Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

LIN7C Polyclonal Antibody - bs-11872R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LIN7C Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11872R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LIN7C Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11872R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LIN7C Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11872R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LIN7C Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11872R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LIN7C Polyclonal Antibody, Cy3 Conjugated - bs-11872R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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