Gene Symbol | PLA1A |
---|---|
Entrez Gene | 51365 |
Alt Symbol | PS-PLA1, PSPLA1 |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A1 member A |
Other Description | phosphatidylserine-specific phospholipase A1alpha |
Swissprots | B2R8V2 B4DXA2 Q53H76 O95991 Q9UPD2 Q86WX6 |
Accessions | EAW79557 EAW79558 EAW79559 EAW79560 Q53H76 AF035268 AAC98921 AF035269 AAC98922 AK222705 BAD96425 AK301880 BAG63314 AK313519 BAG36299 BC035347 BC047703 AAH47703 BE221465 BX647516 DB189568 DB255030 HQ448617 ADQ33095 U37591 AAC99994 XM_006713653 XP_006713716 NM_001206960 NP_001193889 NM_001206961 NP_001193890 NM_015900 NP_056984 NM_001293225 NP_001280154 NR_120610 |
Function | Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production. {ECO:0000269|PubMed:10196188}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney. {ECO:0000269|PubMed:9074642}. |
PLA1A (Y-16) - sc-79675 from Santa Cruz Biotechnology
|
||||||||
PLA1A (H-110) - sc-368597 from Santa Cruz Biotechnology
|
||||||||
PLA1A (K-20) - sc-79672 from Santa Cruz Biotechnology
|
||||||||
Anti-PLA1A antibody - ab139728 from Abcam
|
||||||||
Anti-PLA1A antibody - ab104003 from Abcam
|
||||||||
Anti-PLA1A antibody - ab68976 from Abcam
|
||||||||
Anti-PLA1A antibody - ab196794 from Abcam
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa381-430) - LS-C120218 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366, AP) - LS-C216809 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366, Biotin) - LS-C216811 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366, FITC) - LS-C216812 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366, APC) - LS-C216810 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366, Azide-free, HRP) - LS-C216813 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366, PE) - LS-C216816 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa148-295) - LS-C292498 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa148-295, Biotin) - LS-C297964 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa148-295, Biotin) - LS-C297965 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa148-295, FITC) - LS-C302808 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa148-295, FITC) - LS-C302810 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366) - LS-C324079 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa336-366) - LS-C163754 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa148-295) - LS-C295902 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (C-Terminus) IHC-plus™ - LS-B10189 from LifeSpan Bioscience
|
||||||||
Anti-PSPLA1 / Phospholipase A1 Antibody (aa218-267) IHC-plus™ - LS-B11135 from LifeSpan Bioscience
|
||||||||
PLA1A Antibody - NBP2-32410 from Novus Biologicals
|