PLA1A

Gene Symbol PLA1A
Entrez Gene 51365
Alt Symbol PS-PLA1, PSPLA1
Species Human
Gene Type protein-coding
Description phospholipase A1 member A
Other Description phosphatidylserine-specific phospholipase A1alpha
Swissprots B2R8V2 B4DXA2 Q53H76 O95991 Q9UPD2 Q86WX6
Accessions EAW79557 EAW79558 EAW79559 EAW79560 Q53H76 AF035268 AAC98921 AF035269 AAC98922 AK222705 BAD96425 AK301880 BAG63314 AK313519 BAG36299 BC035347 BC047703 AAH47703 BE221465 BX647516 DB189568 DB255030 HQ448617 ADQ33095 U37591 AAC99994 XM_006713653 XP_006713716 NM_001206960 NP_001193889 NM_001206961 NP_001193890 NM_015900 NP_056984 NM_001293225 NP_001280154 NR_120610
Function Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production. {ECO:0000269|PubMed:10196188}.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney. {ECO:0000269|PubMed:9074642}.

PLA1A CRISPR/Cas9 KO Plasmid (h) - sc-412191 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A HDR Plasmid (h) - sc-412191-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A Double Nickase Plasmid (h) - sc-412191-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A Double Nickase Plasmid (h2) - sc-412191-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A CRISPR Activation Plasmid (h) - sc-412191-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A CRISPR Activation Plasmid (h2) - sc-412191-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A Lentiviral Activation Particles (h) - sc-412191-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A Lentiviral Activation Particles (h2) - sc-412191-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLA1A siRNA (h) - sc-76160 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLA1A shRNA Plasmid (h) - sc-76160-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLA1A shRNA (h) Lentiviral Particles - sc-76160-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16881 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16881 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLA1A siRNA (Human) - CRH9724 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLA1A RNAi - H00051365-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PLA1A (NM_015900.3) - SHH376644 from Creative biogene

Category siRNA
Species Reactivities Human

PLA1A shRNA Plasmid (Human) - CHH9724 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLA1A miRNA 3'UTR clone - MiUTR3H-09239 from Creative biogene

Species Reactivities Human
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