PPP1R3B

Gene Symbol	PPP1R3B
Entrez Gene	79660
Alt Symbol	GL, PPP1R4, PTG
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 1, regulatory subunit 3B
Other Description	PP1 subunit R4|hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL|hepatic glycogen-targeting subunit, G(L)|protein phosphatase 1 regulatory subunit 3B|protein phosphatase 1 regulatory subunit 4|protein phosphatase 1, regulatory (inhibitor) subunit 3B
Swissprots	B3KTV3 Q86XI6 Q9H812
Accessions	CAC69382 EAW65572 Q86XI6 AI078688 AI263711 AK024067 BAB14811 AK091994 AK096119 BAG53215 BC043388 AAH43388 BQ431880 DA100998 DB282578 HQ448647 ADQ33125 XM_006716253 XP_006716316 XM_011543836 XP_011542138 NM_001201329 NP_001188258 NM_024607 NP_078883
Function	Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity). {ECO:0000250}.
Tissue Specificity	Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level). Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart. Weak expression in placenta and lung. {ECO:0000269|PubMed:11872655, ECO:0000269|PubMed:17555403}.
Top Pathways	Insulin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PPP1R4 (G-13) - sc-98085 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PPP1R4 (S-15) - sc-98086 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PTG (H-208) - sc-366229 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-PPP1R3B antibody - ab89105 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-PPP1R3B antibody - ab67043 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-PPP1R3B antibody - C-terminal - ab173856 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody - LS-C155144 from LifeSpan Bioscience Prices $245.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231, APC) - LS-C239357 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231, AP) - LS-C239360 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231, PE) - LS-C239362 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231, FITC) - LS-C239361 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231, Biotin) - LS-C239358 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa204-231) - LS-C324239 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231, Azide-free, HRP) - LS-C248535 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa40-89) - LS-C145520 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-PPP1R3B Antibody (aa205-231) - LS-C158714 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

PPP1R3B Antibody - NBP1-82243 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PPP1R3B Antibody - H00079660-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

PPP1R3B Antibody - NBP1-79917 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B antibody produced in mouse - SAB1407957 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-PPP1R3B (268-280) antibody produced in rabbit - R7406 from Sigma-Aldrich Prices $342.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP1R3B antibody produced in rabbit - HPA028731 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PPP1R3B antibody - N-terminal region (ARP61962_P050) - ARP61962_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PPP1R3B-Antibody-C-term - AP18235b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

GAD65 antibody, Internal - GTX89575 from GeneTex Prices $319.00 Sizes 100 μg Host Goat Clonality Polyclonal

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