PPP1R3B

Gene Symbol	PPP1R3B
Entrez Gene	79660
Alt Symbol	GL, PPP1R4, PTG
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 1, regulatory subunit 3B
Other Description	PP1 subunit R4|hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL|hepatic glycogen-targeting subunit, G(L)|protein phosphatase 1 regulatory subunit 3B|protein phosphatase 1 regulatory subunit 4|protein phosphatase 1, regulatory (inhibitor) subunit 3B
Swissprots	B3KTV3 Q86XI6 Q9H812
Accessions	CAC69382 EAW65572 Q86XI6 AI078688 AI263711 AK024067 BAB14811 AK091994 AK096119 BAG53215 BC043388 AAH43388 BQ431880 DA100998 DB282578 HQ448647 ADQ33125 XM_006716253 XP_006716316 XM_011543836 XP_011542138 NM_001201329 NP_001188258 NM_024607 NP_078883
Function	Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity). {ECO:0000250}.
Tissue Specificity	Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level). Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart. Weak expression in placenta and lung. {ECO:0000269|PubMed:11872655, ECO:0000269|PubMed:17555403}.
Top Pathways	Insulin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PPP1R3B full length protein - ab164065 from Abcam Category Protein Source Wheat germ Species Human

Human PPP1R3B full length protein - ab171709 from Abcam Category Protein Source E. coli Species Human

PPP1R3B Antibody Blocking Peptide - LS-E5699 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPP1R3B Antibody Blocking Peptide - LS-E22625 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPP1R3B Recombinant Protein - H00079660-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PPP1R3B Protein - NBP2-23381 from Novus Biologicals Category Protein Prices $309.00 Sizes 100 µg Species Human

PPP1R3B-Antibody-C-term-Blocking-Peptide - BP18235b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GAD65 blocking peptide - GTX89575-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

LIPF blocking peptide - GTX89300-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Human gL protein - orb246137 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

PPP1R3B Blocking Peptide - 33R-5454 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PPP1R3B protein (His tag) - 80R-3036 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

PPP1R3B (1-285, His-tag) - AR51154PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PPP1R3B (1-285, His-tag) - AR51154PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PPP1R3B - H00079660-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PPP1R3B - H00079660-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PPP1R3B, 1-285aa, Human, His tag, E.coli - 01-P2330 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

PPP1R3B fusion protein - ag5521 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PPP1R3B fusion protein - Ag5734 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PPP1R3B, 1-285aa, Human, His tag, E.coli - GWB-ATG513 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Species Human

Recombinant Human PPP1R3B, His-tagged - PPP1R3B-2330H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human PPP1R3B, GST-tagged - PPP1R3B-1909H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human cytomegalovirus Envelope glycoprotein L(UL115) - CSB-EP515269HWW CSB-BP515269HWW CSB-MP515269HWW from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Protein phosphatase 1 regulatory subunit 3B(PPP1R3B) - CSB-YP769802HU CSB-EP769802HU CSB-BP769802HU CSB-MP769802HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Pseudomonas syringae pv. phaseolicola Aspartyl/glutamyl-tRNA(Asn/Gl - CSB-YP674195PAAT CSB-EP674195PAAT CSB-BP674195PAAT CSB-MP674195PAAT from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Pseudomonas

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