Gene Symbol | RASSF6 |
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Entrez Gene | 166824 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | Ras association (RalGDS/AF-6) domain family member 6 |
Other Description | Ras association (RalGDS/AF-6) domain family 6|putative RAS binding protein|ras association domain-containing protein 6 |
Swissprots | Q86WG9 Q6PDA6 Q86WH0 Q6ZTQ3 Q68DT2 |
Accessions | EAX05685 EAX05686 Q6ZTQ3 AI579909 AK002032 AK126346 BAC86530 AW070877 AW407403 AY217664 AAO61689 AY217665 AAO61690 BC058835 AAH58835 BM923326 BU959014 BX424428 BX957171 CR749283 CAH18138 XM_011531687 XP_011529989 XM_011531688 XP_011529990 XM_011531689 XP_011529991 XM_011531690 XP_011529992 XM_011531691 XP_011529993 XR_938698 NM_001270391 NP_001257320 NM_001270392 NP_001257321 NM_177532 NP_803876 NM_201431 NP_958834 |
Function | Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity). {ECO:0000250}. |
Tissue Specificity | Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart. {ECO:0000269|PubMed:17404571}. |
Top Pathways | Hippo signaling pathway |
RASSF6 (W-14) - sc-104643 from Santa Cruz Biotechnology
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Anti-RASSF6 antibody - ab77706 from Abcam
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Anti-RASSF6 antibody - ab138067 from Abcam
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Anti-RASSF6 Antibody (Internal) - LS-C144438 from LifeSpan Bioscience
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Anti-RASSF6 Antibody (aa135-184) IHC-plus⢠- LS-B11633 from LifeSpan Bioscience
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Anti-RASSF6 Antibody (aa166-179) - LS-C61784 from LifeSpan Bioscience
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Anti-RASSF6 Antibody (aa129-178) - LS-C120300 from LifeSpan Bioscience
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Anti-RASSF6 Antibody (aa113-162) - LS-C200573 from LifeSpan Bioscience
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RASSF6 Antibody - NBP1-85881 from Novus Biologicals
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RASSF6 Antibody - NBP1-00232 from Novus Biologicals
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RASSF6 Antibody - NBP1-68973 from Novus Biologicals
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RASSF6 Polyclonal Antibody - bs-5955R from Bioss
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Anti-RASSF6 antibody produced in rabbit - SAB3501000 from Sigma-Aldrich
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Anti-RASSF6 antibody produced in rabbit - HPA037711 from Sigma-Aldrich
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Anti-RASSF6 antibody produced in rabbit - SAB4500641 from Sigma-Aldrich
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Anti-RASSF6 antibody produced in goat - SAB2500871 from Sigma-Aldrich
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RASSF6 antibody - middle region (ARP59685_P050) - ARP59685_P050 from Aviva Systems Biology
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RASSF6-Antibody - AF1916a from Abgent, a WuXi AppTec company
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RASSF6 Antibody (OAAF04131) - OAAF04131 from Aviva Systems Biology
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RASSF6 Antibody (OAAF07019) - OAAF07019 from Aviva Systems Biology
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RASSF6 antibody - orb75679 from Biorbyt
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RASSF6 Antibody (OAEB01347) - OAEB01347 from Aviva Systems Biology
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RASSF6 antibody - 70R-19789 from Fitzgerald
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RASSF6 Polyclonal Antibody - A5187 from ABclonal
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RASSF6 antibody - 70R-9846 from Fitzgerald
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