Gene Symbol | RASSF6 |
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Entrez Gene | 166824 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | Ras association (RalGDS/AF-6) domain family member 6 |
Other Description | Ras association (RalGDS/AF-6) domain family 6|putative RAS binding protein|ras association domain-containing protein 6 |
Swissprots | Q86WG9 Q6PDA6 Q86WH0 Q6ZTQ3 Q68DT2 |
Accessions | EAX05685 EAX05686 Q6ZTQ3 AI579909 AK002032 AK126346 BAC86530 AW070877 AW407403 AY217664 AAO61689 AY217665 AAO61690 BC058835 AAH58835 BM923326 BU959014 BX424428 BX957171 CR749283 CAH18138 XM_011531687 XP_011529989 XM_011531688 XP_011529990 XM_011531689 XP_011529991 XM_011531690 XP_011529992 XM_011531691 XP_011529993 XR_938698 NM_001270391 NP_001257320 NM_001270392 NP_001257321 NM_177532 NP_803876 NM_201431 NP_958834 |
Function | Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity). {ECO:0000250}. |
Tissue Specificity | Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart. {ECO:0000269|PubMed:17404571}. |
Top Pathways | Hippo signaling pathway |
RASSF6 Antibody Blocking Peptide - LS-E21833 from LifeSpan Bioscience
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RASSF6 Antibody Blocking Peptide - LS-E26648 from LifeSpan Bioscience
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RASSF6 Antibody Blocking Peptide - LS-E31183 from LifeSpan Bioscience
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RASF6-Antibody-C-term-Blocking-peptide - BP10404b from Abgent, a WuXi AppTec company
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RASSF6 blocking peptide - GTX88787-PEP from GeneTex
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RASSF6 Blocking Peptide - 33R-9527 from Fitzgerald
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RASSF6 Peptide - AC21-1484-P from Abcore
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RASSF6 (Center) Control Peptide - AP55594CP-N from Acris Antibodies
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RASSF6 Peptide - 6543P from ProSci
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RASSF6 Peptide - 46-705P from ProSci
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RASSF6 fusion protein - ag2565 from Proteintech Group
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Recombinant Human Ras association domain-containing protein 6(RASSF6) - CSB-YP754570HU CSB-EP754570HU CSB-BP754570HU CSB-MP754570HU from Cusabio
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RASSF6, Peptide - MBS426247 from MyBioSource
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RASSF6 Peptide, Human - M34GP13014H from Creative Peptides
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Ras association domain-containing protein 6 (RASSF6), Recombinant Protein - MBS1345061 from MyBioSource
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RASSF6 Recombinant Protein (Human) (OPCA05036) - OPCA05036 from Aviva Systems Biology
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RASSF6 Recombinant Protein Antigen - NBP2-55145PEP from Novus Biologicals
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Human RASSF6 protein - orb54549 from Biorbyt
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RASSF6 Immunizing peptide - orb50416 from Biorbyt
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Recombinant Human RASSF6 Protein (1-303 aa), GST-tagged - RASSF6-2153H from Creative Biomart
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