LRRC7

Gene Symbol LRRC7
Entrez Gene 57554
Alt Symbol DENSIN
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 7
Other Description densin-180|leucine-rich repeat-containing protein 7
Swissprots Q5VXC3 Q5VXC2 Q8WX20 Q9P2I2 Q86VE8 Q68D07 Q96NW7
Accessions EAX06461 EAX06462 EAX06463 EAX06464 EAX06465 Q96NW7 AB037786 BAA92603 AF434715 AAL28133 AF498274 AAP06801 AK294206 BAH11697 BC080568 BC128989 AAI28990 CR749629 CAH18423 XM_011541836 XP_011540138 NM_020794 NP_065845
Function Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. {ECO:0000269|PubMed:11729199}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11729199}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}.
Tissue Specificity Brain-specific. Isoform 3 is ubiquitously expressed. {ECO:0000269|PubMed:12525888}.

densin-180 (G-1) - sc-390153 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
densin-180 (G-1): sc-390153. Western blot analysis of densin-180 expression in mouse brain tissue extract.

densin-180 (R-16) - sc-15447 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
densin-180 (R-16): sc-15447. Western blot analysis of densin-180 expression in human bladder tissue extract.

densin-180 (R-300) - sc-28947 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
densin-180 (R-300): sc-28947. Western blot analysis of densin-180 expression in rat brain tissue extract.

Anti-LAP1 antibody - ab104918 from Abcam

Host Rabbit
Clonality Polyclonal
ICC/IF image of ab104918 stained PC12 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab104918 at 1/200 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-LAP1 antibody - ab115168 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry Image of Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ab115168 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-LAP1 antibody - ab56016 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAP1 antibody [RL13] - ab2737 from Abcam

Prices $370.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone RL13
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) was performed on rat breast tissue. Antigen retreived was performed using 10mM sodium citrate followed by microwave treatment for 8-15 minutes. Endogenous peroxidases were blocked in 3% H202-methanol for 15 minutes and tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Cells were incubated with ab2737 (1:50) overnight in a humidified chamber. Tissues were washed in PBST and detection was performed using a secondary antibody conjugated to HRP. DAB staining buffer was applied and tissues were counterstained with hematoxylin and prepped for mounting. Images were taken at 40X magnification.

Anti-LAP1 antibody - Aminoterminal end - ab56040 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAP1 / LRRC7 Antibody (C-Terminus) - LS-C47075 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAP1 / LRRC7 Antibody (aa1235-1284) - LS-C151842 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LAP1 / LRRC7 antibody Western Blot of Jurkat.

Anti-LAP1 / LRRC7 Antibody (N-Terminus) IHC-plus™ - LS-B2825 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LRRC7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2825 concentration 5 ug/ml.

LRRC7 Antibody - NBP1-90593 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LRRC7 Antibody [NBP1-90593] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).

LRRC7 Antibody - NBP1-90594 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/ Immunofluorescence: LRRC7 Antibody [NBP1-90594] - Staining of human cell line U-2 OS shows positivity in nucleoli & cytoplasm.

LRRC7 Antibody - NBP1-46528 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC7 antibody produced in rabbit - HPA005625 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LRRC7: <B>Cat. No. HPA005625</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra.

Anti-LRRC7 antibody produced in rabbit - HPA002314 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LRRC7: <B>Cat. No. HPA002314</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human appendix tissue showing cytoplasmic and/or membranous staining of lymphoid cells as well as some luminal positivity in glandular cells.

LRRC7 antibody - C-terminal region (ARP64881_P050) - ARP64881_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LAP1 antibody - GTX85708 from GeneTex

Prices $289.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-LRRC7 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX85708

LRRC7 Antibody (OALA02908) - OALA02908 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

LRRC7 (N-term) antibody - AP09006PU-N from Acris Antibodies

Prices $430.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

LRRC7 antibody - PAB5429 from Acris Antibodies

Prices $420.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LRRC7 antibody - PAB5430 from Acris Antibodies

Prices $420.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LRRC7 Antibody - 51-134 from ProSci

Prices $375.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry staining of LRRC7 in brain cortex tissue using LRRC7 Antibody.

Leucine Rich Repeat Containing 7 (LRRC7) Rabbit anti-Human Polyclonal (N-Terminus) Antibody - GWB-CADF7C from Genway Biotech

Prices $483.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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