STK10

Gene Symbol	STK10
Entrez Gene	6793
Alt Symbol	LOK, PRO2729
Species	Human
Gene Type	protein-coding
Description	serine/threonine kinase 10
Other Description	lymphocyte-oriented kinase|serine/threonine-protein kinase 10
Swissprots	Q6NSK0 A6ND35 O94804 B3KMY1 B2R8F5 Q9UIW4
Accessions	EAW61439 O94804 AB015718 BAA35073 AF119894 AAF69648 AI584023 AK022960 BAG51143 AK092814 AK307943 AK313350 BAG36152 AL133081 CAB61400 BC014413 BC070077 AAH70077 BI459912 DA507768 DB068209 XM_011534641 XP_011532943 XM_011534642 XP_011532944 XM_011534643 XP_011532945 XM_011534644 XP_011532946 NM_005990 NP_005981
Function	Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo. {ECO:0000269|PubMed:11903060, ECO:0000269|PubMed:12639966, ECO:0000269|PubMed:19255442}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19255442}; Peripheral membrane protein {ECO:0000269|PubMed:19255442}.
Tissue Specificity	Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung. {ECO:0000269|PubMed:12639966}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LOK (D-6) - sc-398083 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

LOK (F-24) - sc-130805 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

LOK (E-18) - sc-83151 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

LOK (C-17) - sc-83150 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-LOK antibody - ab37727 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-LOK antibody - ab70483 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LOK antibody - ab70484 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LOK antibody - ab138315 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-LOK antibody - ab89675 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus, AP) - LS-C220793 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus, APC) - LS-C220794 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus, Biotin) - LS-C220795 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus, FITC) - LS-C220796 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus, Azide-free, HRP) - LS-C220797 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (N-Terminus, AP) - LS-C220799 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus, PE) - LS-C220798 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (N-Terminus, Biotin) - LS-C220800 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (N-Terminus, APC) - LS-C220801 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (N-Terminus, FITC) - LS-C220802 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (N-Terminus, Azide-free, HRP) - LS-C220803 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (N-Terminus, PE) - LS-C220804 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus) - LS-C287291 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (aa667-696) - LS-C164579 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (aa667-696) - LS-C325449 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STK10 / LOK Antibody (C-Terminus) - LS-C328778 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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