STK10

Gene Symbol STK10
Entrez Gene 6793
Alt Symbol LOK, PRO2729
Species Human
Gene Type protein-coding
Description serine/threonine kinase 10
Other Description lymphocyte-oriented kinase|serine/threonine-protein kinase 10
Swissprots Q6NSK0 A6ND35 O94804 B3KMY1 B2R8F5 Q9UIW4
Accessions EAW61439 O94804 AB015718 BAA35073 AF119894 AAF69648 AI584023 AK022960 BAG51143 AK092814 AK307943 AK313350 BAG36152 AL133081 CAB61400 BC014413 BC070077 AAH70077 BI459912 DA507768 DB068209 XM_011534641 XP_011532943 XM_011534642 XP_011532944 XM_011534643 XP_011532945 XM_011534644 XP_011532946 NM_005990 NP_005981
Function Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo. {ECO:0000269|PubMed:11903060, ECO:0000269|PubMed:12639966, ECO:0000269|PubMed:19255442}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:19255442}; Peripheral membrane protein {ECO:0000269|PubMed:19255442}.
Tissue Specificity Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung. {ECO:0000269|PubMed:12639966}.

Active human LOK protein fragment - ab55710 from Abcam

Category Protein
Prices $302.00, $1,845.00
Sizes 10 µg, 100 µg
Source Baculovirus infected sf9 cells
Species Human

Human LOK protein fragment - ab131984 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE, stained with Coomassie Blue showing ab131984.

Human LOK protein fragment - ab159607 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159607 on a 12.5% SDS-PAGE stained with Coomassie Blue.

STK10 / LOK Antibody Blocking Peptide - LS-E3455 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

STK10 / LOK Antibody Blocking Peptide - LS-E27854 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

STK10 / LOK Antibody Blocking Peptide - LS-E9393 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human LOK Protein - H00006793-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human LOK Protein - H00006793-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

LOK-Antibody-C-term-E707-Blocking-Peptide - BP7959b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human STK10 His tag protein - orb83829 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source E. coli
Species Human
SDS-PAGE analysis of human STK10 His tag protein

STK10 peptide - orb217984 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human

LOK Blocking Peptide - abx063315 from Abbexa

Category Peptide
Species Human

STK10 / LOK - H00006793-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

STK10 / LOK - H00006793-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

STK10 / LOK - H00006793-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

STK10 / LOK - H00006793-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

STK10 / LOK - P5578 from Acris Antibodies

Category Protein
Prices $1,010.00
Sizes 5 µg
Species Human

STK10 fusion protein - ag1607 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

STK10 fusion protein - Ag22169 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Lok1/Stk10, Active Human Recombinant Protein - GWB-88ED64 from Genway Biotech

Category Protein
Prices $410.00
Sizes 10 µg
Species Human
Lok1/Stk10, Active Human Recombinant Protein

Recombinant Human Serine/Threonine Kinase 10, GST-tagged, Active - STK10-343H from Creative Biomart

Category Protein
Source Sf9 insect cells using baculovirus.

Recombinant Human STK10, His tagged - STK10-765H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human Serine/Threonine Kinase 10, His-tagged - STK10-555H from Creative Biomart

Category Protein
Source Sf9 insect cells.

LOK Protein, active, 250 µg - 14-686M from EMD Millipore

Category Protein
Prices $2,441.00
Sizes 250 µg also available in 10 μg size . (cat#14-686) and in bulk (cat#14-686-K)
Source expressed by baculovirus in Sf21 cells

LOK Blocking Peptide - CBP2121 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human
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