STK10

Gene Symbol STK10
Entrez Gene 6793
Alt Symbol LOK, PRO2729
Species Human
Gene Type protein-coding
Description serine/threonine kinase 10
Other Description lymphocyte-oriented kinase|serine/threonine-protein kinase 10
Swissprots Q6NSK0 A6ND35 O94804 B3KMY1 B2R8F5 Q9UIW4
Accessions EAW61439 O94804 AB015718 BAA35073 AF119894 AAF69648 AI584023 AK022960 BAG51143 AK092814 AK307943 AK313350 BAG36152 AL133081 CAB61400 BC014413 BC070077 AAH70077 BI459912 DA507768 DB068209 XM_011534641 XP_011532943 XM_011534642 XP_011532944 XM_011534643 XP_011532945 XM_011534644 XP_011532946 NM_005990 NP_005981
Function Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo. {ECO:0000269|PubMed:11903060, ECO:0000269|PubMed:12639966, ECO:0000269|PubMed:19255442}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:19255442}; Peripheral membrane protein {ECO:0000269|PubMed:19255442}.
Tissue Specificity Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung. {ECO:0000269|PubMed:12639966}.

LOK CRISPR/Cas9 KO Plasmid (h) - sc-405859 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK HDR Plasmid (h) - sc-405859-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK Double Nickase Plasmid (h) - sc-405859-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK Double Nickase Plasmid (h2) - sc-405859-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK CRISPR Activation Plasmid (h) - sc-405859-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK CRISPR Activation Plasmid (h2) - sc-405859-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK Lentiviral Activation Particles (h) - sc-405859-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK Lentiviral Activation Particles (h2) - sc-405859-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK siRNA (h) - sc-75685 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LOK shRNA Plasmid (h) - sc-75685-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LOK shRNA (h) Lentiviral Particles - sc-75685-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU153771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK2133 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2134 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2132 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN20728 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20728 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

STK10 siRNA (Human) - CRH4648 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LOK RNAi - H00006793-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

STK10 - MBS8217237 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LOK CRISPR/Cas9 KO Plasmid (h2) - sc-405859-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LOK HDR Plasmid (h2) - sc-405859-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human STK10 (NM_005990.3) - SHH419676 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human STK10(NM_005990.3) - SHL033996 from Creative biogene

Category siRNA
Species Reactivities Human

Human STK10 siRNA - orb265150 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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