SRGAP3

Gene Symbol	SRGAP3
Entrez Gene	9901
Alt Symbol	ARHGAP14, MEGAP, SRGAP2, WRP
Species	Human
Gene Type	protein-coding
Description	SLIT-ROBO Rho GTPase activating protein 3
Other Description	SLIT-ROBO Rho GTPase activating protein 2|SLIT-ROBO Rho GTPase-activating protein 3|WAVE-associated Rac GTPase activating protein|mental disorder-associated GAP|rho GTPase-activating protein 14
Swissprots	Q8IX13 Q8IZV8 O43295
Accessions	EAW63950 EAW63951 O43295 AB007871 BAA24841 AB032982 BAA86470 AF427144 AAN07095 AF464189 AAN57784 AK054831 AK094355 AK126331 AU120948 BC039300 AAH39300 BC140004 BC172359 AAI72359 BM976179 DA532895 HG495444 HG495445 HG495446 HG495447 HG495448 XM_011534295 XP_011532597 XM_011534296 XP_011532598 XM_011534297 XP_011532599 XM_011534298 XP_011532600 XM_011534299 XP_011532601 XM_011534300 XP_011532602 XM_011534301 XP_011532603 XM_011534302 XP_011532604 XM_011534303 XP_011532605 XR_427300 NM_001033116 NM_001033117 NP_001028289 NM_014850 NP_055665
Function	GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. {ECO:0000269|PubMed:12195014, ECO:0000269|PubMed:12447388}.
Tissue Specificity	Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain. {ECO:0000269|PubMed:12195014, ECO:0000269|PubMed:12447388}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human srGAP3 peptide - ab74595 from Abcam Category Peptide

Human srGAP3 protein fragment - ab132714 from Abcam Category Protein Source Wheat germ Species Human

ARHGAP14 / SRGAP3 - H00009901-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ARHGAP14 / SRGAP3 - H00009901-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SRGAP3 fusion protein - Ag3516 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SRGAP3, GST-tagged - SRGAP3-2951H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SLIT-ROBO Rho GTPase-activating protein 3(SRGAP3) ,partial - CSB-YP022663HU CSB-EP022663HU CSB-BP022663HU CSB-MP022663HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ARHGAP14 / SRGAP3 (transcript variant 1) - TP314288 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SRGAP3-Blocking-Peptide-C-term - BP21672b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLIT-ROBO Rho GTPase-activating protein 3 (SRGAP3), partial, Recombinant Protein - MBS1257369 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SRGAP3-BRAF, Recombinant Protein - MBS515459 from MyBioSource Category Protein Prices $315.00, $425.00 Sizes 5 µg, 10 µg Source Sf9 insect cells using baculovirus Species Human

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