SRGAP3

Gene Symbol SRGAP3
Entrez Gene 9901
Alt Symbol ARHGAP14, MEGAP, SRGAP2, WRP
Species Human
Gene Type protein-coding
Description SLIT-ROBO Rho GTPase activating protein 3
Other Description SLIT-ROBO Rho GTPase activating protein 2|SLIT-ROBO Rho GTPase-activating protein 3|WAVE-associated Rac GTPase activating protein|mental disorder-associated GAP|rho GTPase-activating protein 14
Swissprots Q8IX13 Q8IZV8 O43295
Accessions EAW63950 EAW63951 O43295 AB007871 BAA24841 AB032982 BAA86470 AF427144 AAN07095 AF464189 AAN57784 AK054831 AK094355 AK126331 AU120948 BC039300 AAH39300 BC140004 BC172359 AAI72359 BM976179 DA532895 HG495444 HG495445 HG495446 HG495447 HG495448 XM_011534295 XP_011532597 XM_011534296 XP_011532598 XM_011534297 XP_011532599 XM_011534298 XP_011532600 XM_011534299 XP_011532601 XM_011534300 XP_011532602 XM_011534301 XP_011532603 XM_011534302 XP_011532604 XM_011534303 XP_011532605 XR_427300 NM_001033116 NM_001033117 NP_001028289 NM_014850 NP_055665
Function GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. {ECO:0000269|PubMed:12195014, ECO:0000269|PubMed:12447388}.
Tissue Specificity Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain. {ECO:0000269|PubMed:12195014, ECO:0000269|PubMed:12447388}.
Top Pathways Axon guidance

WRP CRISPR/Cas9 KO Plasmid (h) - sc-407459 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP HDR Plasmid (h) - sc-407459-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP Double Nickase Plasmid (h) - sc-407459-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP Double Nickase Plasmid (h2) - sc-407459-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP CRISPR Activation Plasmid (h) - sc-407459-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP CRISPR Activation Plasmid (h2) - sc-407459-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP Lentiviral Activation Particles (h) - sc-407459-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP Lentiviral Activation Particles (h2) - sc-407459-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WRP siRNA (h) - sc-76929 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WRP shRNA Plasmid (h) - sc-76929-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WRP shRNA (h) Lentiviral Particles - sc-76929-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU061921 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20572 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20572 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SRGAP3 siRNA (Human) - CRH6646 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRGAP3 - MBS829616 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SRGAP3 (NM_014850.3) - SHH417824 from Creative biogene

Category siRNA
Species Reactivities Human

Human SRGAP3 siRNA - orb267148 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRGAP3 shRNA Plasmid (Human) - CHH6646 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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