SNX9

Gene Symbol	SNX9
Entrez Gene	51429
Alt Symbol	SDP1, SH3PX1, SH3PXD3A, WISP
Species	Human
Gene Type	protein-coding
Description	sorting nexin 9
Other Description	SH3 and PX domain-containing protein 1|SH3 and PX domain-containing protein 3A|Wiskott-Aldrich syndrome protein (WASP) interactor protein|sorting nexin-9
Swissprots	Q9UJH6 Q9BVM1 Q9UP20 Q9BSI7 Q9Y5X1
Accessions	EAW47668 EAW47669 Q9Y5X1 AB209736 BAD92973 AF001629 AAD00898 AF076957 AAD43001 AF121859 AAD27832 AF131214 AAF04473 AF172847 AAL54871 AF190158 AAQ13702 AJ420452 AJ420512 AK026637 AK127345 BAG54490 AK314360 BAG36992 BC001084 AAH01084 BC005022 AAH05022 BG766499 DA315945 DA336311 DQ893300 ABM84226 DQ896789 ABM87788 XM_005267015 XP_005267072 XM_011535886 XP_011534188 NM_016224 NP_057308
Function	Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F- actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate. {ECO:0000269|PubMed:11799118, ECO:0000269|PubMed:12952949, ECO:0000269|PubMed:15703209, ECO:0000269|PubMed:17609109, ECO:
Subcellular Location	Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin- coated vesicle. Golgi apparatus, trans-Golgi network. Cell projection, ruffle. Cytoplasm. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation. Colocalizes with the actin cytoskeleton at the cell membrane.
Tissue Specificity	Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:10531379}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNX9 / WISP ELISA Kit (Sandwich ELISA) - LS-F9129 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.052 ng/ml Range 0.156-10 ng/ml

Human SNX9 / WISP ELISA Kit (Sandwich ELISA) - LS-F12627 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.156-10 ng/ml

Sorting nexin-9, SNX9, Human, ELISA Kit - E11356h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

SNX9 (Human) IP-WB Antibody Pair - H00051429-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SNX9 (Human) IP-WB Antibody Pair - H00051429-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Sorting Nexin 9, ELISA Kit - MBS084497 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9, ELISA Kit - MBS081948 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9, ELISA Kit - MBS099168 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9, ELISA Kit - MBS087413 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9, ELISA Kit - MBS074941 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9, ELISA Kit - MBS099297 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9, ELISA Kit - MBS103913 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sorting Nexin 9 (SNX9), ELISA Kit - MBS2022749 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human SNX9 is typically less than 0.052ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

ELISA Kit for Sorting Nexin 9 (SNX9) - SEE879Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.052ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse SNX9 / WISP ELISA Kit (Custom ELISA) - LS-F16141 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Sorting Nexin 9 (SNX9) ELISA Kit - EKU07420 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.052 ng/mL Range 0.156-10 ng/mL

Human Sorting Nexin 9 ELISA Kit - abx153141 from Abbexa Category ELISA Kit Sensitivity 0.052 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Sorting nexin-9 ELISA Kit - abx250556 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Sorting Nexin 9 (SNX9), Human, ELISA Kit - DL-SNX9-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human SNX9 ELISA Kit - abx571683 from Abbexa Category ELISA Kit Sensitivity 0.052 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Sorting nexin-9 ELISA Kit - EKE53162 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.12 ng/ml Range 0.312-20 ng/mL

SNX9 - EKH2584 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

SNX9 ELISA Kit (Human) (OKEH02157) - OKEH02157 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.12 ng/mL Range 0.312 - 20 ng/mL

Human SNX9 ELISA Kit - E036236 from Biobool Category ELISA Kit

Human Sorting nexin-9 ELISA Kit - EK2816 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.12ng/ml Range 0.312-20 ng/mL

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