Gene Symbol | PLXNB1 |
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Entrez Gene | 5364 |
Alt Symbol | PLEXIN-B1, PLXN5, SEP |
Species | Human |
Gene Type | protein-coding |
Description | plexin B1 |
Other Description | plexin 5|plexin-B1|semaphorin receptor SEP |
Swissprots | Q6NY20 Q9UJ92 Q9UIV7 A6H8Y2 Q9UJ93 O43157 |
Accessions | EAW64864 EAW64865 EAW64866 O43157 AB007867 BAA23703 AJ011414 CAB56221 AJ011415 CAB56222 AK091832 BAG52423 AK092609 BAG52582 AK296776 BAG59355 BC066773 BC128094 AAI28095 BC129947 BC146793 AAI46794 LN626690 CEH24705 X87904 CAB57277 XM_011533832 XP_011532134 XM_011533833 XP_011532135 XM_011533834 XP_011532136 XM_011533835 XP_011532137 XM_011533836 XP_011532138 XM_011533837 XP_011532139 XR_940457 XR_940458 NM_001130082 NP_001123554 NM_002673 NP_002664 |
Function | Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. {ECO:0000269|PubMed:12196628, ECO:0000269|PubMed:12198496, ECO:0000269|PubMed:15210733, ECO:0000269|PubMed:19843518, ECO:0000269|PubMed:20877282, ECO:0000269|PubMed:21912513}. |
Subcellular Location | Isoform 3: Secreted. |
Tissue Specificity | Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver. {ECO:0000269|PubMed:8570614}. |
Top Pathways | Axon guidance |
Human Plexin B1 peptide - ab41062 from Abcam
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Human Plexin B1 peptide - ab41063 from Abcam
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Plexin B1 peptide - ab196855 from Abcam
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Human Plexin B1 Protein - abx068612 from Abbexa
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Human Plexin B1 Protein - abx068611 from Abbexa
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Human Plexin B1 Protein - abx068613 from Abbexa
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Plexin B1 (PLXNB1), Human - 20-9258 from ARP American Research Products
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Plexin B1 (PLXNB1), Human - 20-9259 from ARP American Research Products
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Plexin B1 (PLXNB1), Human - 20-9260 from ARP American Research Products
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PLXNB1 fusion protein - ag20719 from Proteintech Group
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PLXNB1 fusion protein - ag16262 from Proteintech Group
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Recombinant Plexin B1 (PLXNB1) - RPH358Hu01 from Uscn Life Science Inc.
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Recombinant Plexin B1 (PLXNB1) - RPH358Hu02 from Uscn Life Science Inc.
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Recombinant Plexin B1 (PLXNB1) - RPH358Hu03 from Uscn Life Science Inc.
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Recombinant Plexin B1 (PLXNB1) - RPH358Mu01 from Uscn Life Science Inc.
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Recombinant Plexin B1 (PLXNB1) - RPH358Hu01 from Cloud-clone
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Recombinant Plexin B1 (PLXNB1) - RPH358Hu02 from Cloud-clone
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Recombinant Plexin B1 (PLXNB1) - RPH358Hu03 from Cloud-clone
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Recombinant Human Plexin-B1(PLXNB1) ,partial - CSB-YP018222HU CSB-EP018222HU CSB-BP018222HU CSB-MP018222HU from Cusabio
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Plexin B1 (C-terminal region) - PX1845 from ECM Biosciences
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Plexin B1 (PLXNB1) - RPU143361 from Biomatik
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Plexin B1 (PLXNB1) - RPU143362 from Biomatik
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Plexin B1 (PLXNB1) - RPU143363 from Biomatik
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Plexin B1, Recombinant Protein - MBS2029252 from MyBioSource
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Plexin B1 (PLXNB1), Recombinant Protein - MBS2009903 from MyBioSource
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