PELI2

Gene Symbol PELI2
Entrez Gene 57161
Alt Symbol -
Species Human
Gene Type protein-coding
Description pellino E3 ubiquitin protein ligase family member 2
Other Description E3 ubiquitin-protein ligase pellino homolog 2|pellino homolog 2|pellino-2|protein pellino homolog 2
Swissprots B2RDY5 Q9HAT8
Accessions EAW80689 Q9HAT8 AF302502 AAG15390 AK025208 BAB15084 AK315727 BAG38082 AL133605 CAH56388 AL709755 BC009476 AAH09476 XM_005267890 XP_005267947 XM_006720211 XP_006720274 XM_011536990 XP_011535292 XM_011536991 XP_011535293 XM_011536992 XP_011535294 NM_021255 NP_067078
Function E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. {ECO:0000269|PubMed:12804775, ECO:0000269|PubMed:12860405, ECO:0000269|PubMed:17675297, ECO:0000269|PubMed:17997719, ECO:0000269|PubMed:22669975}.

Pellino 1/2 (F-7) - sc-271065 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pellino 1/2 (F-7): sc-271065. Western blot analysis of Pellino 1/2 expression in Ramos (A) and NAMALWA (B) whole cell lysates.

Pellino 1/2 (H-105) - sc-67025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pellino 1/2 (H-105): sc-67025. Western blot analysis of Pellino 1/2 expression in HeLa whole cell lysate.

Pellino 2 (C-13) - sc-31621 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pellino 2 (C-13): sc-31621. Western blot analysis of Pellino 2 expression in Ramos whole cell lysate.

Anti-Pellino 2 antibody - ab126982 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Pellino 2 antibody (ab126982) at 1/500 dilution + HeLa whole cell lysate at 30 µg

Anti-Pellino 2 antibody - N-terminal - ab192789 from Abcam

Prices $407.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human testis tissue labeling Pellino 2 with ab192789 at 1/100.

Anti-Pellino 2 antibody - N-terminal - ab171330 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Pellino 2 antibody - N-terminal (ab171330) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-PELI2 / Pellino 2 Antibody (aa15-43) IHC-plus™ - LS-B10949 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-PELI2 / Pellino 2 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10949 dilution 1:100.

Anti-PELI2 / Pellino 2 Antibody (aa323-335) - LS-C38128 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa323-335) - LS-C147866 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51, APC) - LS-C284527 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51, AP) - LS-C284528 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51, Biotin) - LS-C284529 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51, FITC) - LS-C284530 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51, PE) - LS-C284534 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51, Azide-free, HRP) - LS-C284533 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PELI2 / Pellino 2 Antibody (aa22-51) - LS-C323932 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Pellino 2 Antibody - NBP2-33679 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Pellino 2 Antibody - NBP2-15068 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Pellino 2 Antibody - H00057161-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Pellino 2 Antibody [H00057161-B01P] - Analysis of PELI2 expression in transfected 293T cell line by PELI2 polyclonal antibody. Lane 1: PELI2 transfected lysate(46.2 KDa). Lane 2: Non-transfected lysate.

ANTI-PELI2 (N-TERM) antibody produced in rabbit - SAB1304496 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PELI2 (N-term): <B>Cat. No. SAB1304496</B>: PELI2 Antibody (N-term) western blot analysis in HEK_293 cell line lysates (35 μg/lane).

Anti-PELI2 (172-185) antibody produced in rabbit - SAB1104387 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human PELI2 was separated on SDS-PAGE, blotted with Anti-PELI2 (172-185) (<B>Cat. No. SAB1104387</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-PELI2 antibody produced in rabbit - HPA053182 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PELI2: <B>Cat. No. HPA053182</B>: Immunohistochemical staining of Human nasopharynx shows strong membranous and nuclear positivity in respiratory epithelial cells.

Anti-PELI2 antibody produced in mouse - SAB1407776 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PELI2: <B>Cat. No. SAB1407776</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~46.2 kDa using PELI2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PELI2 antibody produced in rabbit - SAB2701284 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PELI2: <B>Cat. No. SAB2701284</B>: Western Blot analysis of PELI2 in extracts from <B>Lanes</B><BR/>A. HeLa using <B>Cat. No. SAB2701284</B> at a 1:500 dilution.

PELI2-Antibody-N-term - AP12838a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PELI2 Antibody (N-term) (Cat. #AP12838a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PELI2 antibody detected the PELI2 protein (arrow).
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