PELI2

Gene Symbol PELI2
Entrez Gene 57161
Alt Symbol -
Species Human
Gene Type protein-coding
Description pellino E3 ubiquitin protein ligase family member 2
Other Description E3 ubiquitin-protein ligase pellino homolog 2|pellino homolog 2|pellino-2|protein pellino homolog 2
Swissprots B2RDY5 Q9HAT8
Accessions EAW80689 Q9HAT8 AF302502 AAG15390 AK025208 BAB15084 AK315727 BAG38082 AL133605 CAH56388 AL709755 BC009476 AAH09476 XM_005267890 XP_005267947 XM_006720211 XP_006720274 XM_011536990 XP_011535292 XM_011536991 XP_011535293 XM_011536992 XP_011535294 NM_021255 NP_067078
Function E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. {ECO:0000269|PubMed:12804775, ECO:0000269|PubMed:12860405, ECO:0000269|PubMed:17675297, ECO:0000269|PubMed:17997719, ECO:0000269|PubMed:22669975}.

Pellino 2 CRISPR/Cas9 KO Plasmid (h) - sc-402305 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 HDR Plasmid (h) - sc-402305-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 Double Nickase Plasmid (h) - sc-402305-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 Double Nickase Plasmid (h2) - sc-402305-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 CRISPR Activation Plasmid (h) - sc-402305-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 CRISPR Activation Plasmid (h2) - sc-402305-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 Lentiviral Activation Particles (h) - sc-402305-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 Lentiviral Activation Particles (h2) - sc-402305-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pellino 2 siRNA (h) - sc-44402 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pellino 2 shRNA Plasmid (h) - sc-44402-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pellino 2 shRNA (h) Lentiviral Particles - sc-44402-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU132231 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16615 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16615 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PELI2 siRNA (Human) - CRJ1368 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PELI2 (NM_021255.2) - SHH373444 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PELI2(NM_021255.2) - SHR095170 from Creative biogene

Category siRNA
Species Reactivities Human

Human PELI2 siRNA - orb271869 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PELI2 shRNA Plasmid (Human) - CHJ1368 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PELI2 miRNA 3'UTR clone - MiUTR1H-07778 from Creative biogene

Species Reactivities Human
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