Gene Symbol | PTGDR |
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Entrez Gene | 5729 |
Alt Symbol | AS1, ASRT1, DP, DP1, PTGDR1 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin D2 receptor (DP) |
Other Description | PGD2 receptor|prostaglandin D2 receptor |
Swissprots | Q13250 Q1ZZ52 Q13251 G3V5L3 Q13258 |
Accessions | AAC50176 AAC50178 ABD72608 EAW65657 Q13258 AK026202 BC040968 AAH40968 CD013871 EF577397 ABQ52417 U31099 AAC50177 XM_005267891 XP_005267948 NM_000953 NP_000944 NM_001281469 NP_001268398 |
Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes. {ECO:0000269|PubMed:11082108, ECO:0000269|PubMed:6302737}. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human Prostaglandin D2 Receptor full length protein - ab117045 from Abcam
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Prostaglandin D2 Receptor peptide - ab111326 from Abcam
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TFDP1 Antibody Blocking Peptide - LS-E10859 from LifeSpan Bioscience
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TFDP1 Antibody Blocking Peptide - LS-E10860 from LifeSpan Bioscience
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TFDP1 Antibody Blocking Peptide - LS-E10652 from LifeSpan Bioscience
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TFDP1 Antibody Blocking Peptide - LS-E14014 from LifeSpan Bioscience
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Prostaglandin D2 Receptor Antibody Blocking Peptide - LS-E28714 from LifeSpan Bioscience
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Prostaglandin D2 Receptor Antibody Blocking Peptide - LS-E29024 from LifeSpan Bioscience
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Prostaglandin D2 Receptor Antibody Blocking Peptide - LS-E28979 from LifeSpan Bioscience
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Prostaglandin D2 Receptor Antibody Blocking Peptide - LS-E22420 from LifeSpan Bioscience
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Prostaglandin D2 Receptor Antibody Blocking Peptide - LS-E29337 from LifeSpan Bioscience
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Recombinant Human PTGDR Protein - H00005729-P01 from Novus Biologicals
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PTGDR Blocking Peptide - 33R-2946 from Fitzgerald
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PTGDR Blocking Peptide - 33R-8342 from Fitzgerald
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PTGDR - H00005729-G01 from Acris Antibodies
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PTGDR - H00005729-P01-10 from Acris Antibodies
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PTGDR - H00005729-P01-25 from Acris Antibodies
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PTGDR Control Peptide - SP4457CP from Acris Antibodies
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Recombinant Human PTGDR - PTGDR-31204TH from Creative Biomart
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ChemiSCREEN™ Human DP Prostanoid Receptor Membrane Preparation - HTS091M from EMD Millipore
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PD2R (E301) Peptide - BS3239P from Bioworld Technology
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Recombinant Human PTGDR Protein - H00005729-G01 from Novus Biologicals
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Recombinant Transcription Factor Dp1 (TFDP1) - RPM355Hu01 from Cloud-clone
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PGD2 Receptor Blocking Peptide - abx162004 from Abbexa
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PTGDR Peptide, Human - M34GP12654H from Creative Peptides
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