Gene Symbol | PTGDR |
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Entrez Gene | 5729 |
Alt Symbol | AS1, ASRT1, DP, DP1, PTGDR1 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin D2 receptor (DP) |
Other Description | PGD2 receptor|prostaglandin D2 receptor |
Swissprots | Q13250 Q1ZZ52 Q13251 G3V5L3 Q13258 |
Accessions | AAC50176 AAC50178 ABD72608 EAW65657 Q13258 AK026202 BC040968 AAH40968 CD013871 EF577397 ABQ52417 U31099 AAC50177 XM_005267891 XP_005267948 NM_000953 NP_000944 NM_001281469 NP_001268398 |
Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes. {ECO:0000269|PubMed:11082108, ECO:0000269|PubMed:6302737}. |
Top Pathways | Neuroactive ligand-receptor interaction |
DP (C-15) - sc-55812 from Santa Cruz Biotechnology
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DP (H-48) - sc-67277 from Santa Cruz Biotechnology
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DP (N-14) - sc-55817 from Santa Cruz Biotechnology
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DP (M-47) - sc-67278 from Santa Cruz Biotechnology
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HLA-DR/DP/DQ/DX (CR3/43) - sc-53302 from Santa Cruz Biotechnology
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Anti-Prostaglandin D2 Receptor antibody - ab99446 from Abcam
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Anti-Prostaglandin D2 Receptor antibody - ab77650 from Abcam
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Anti-Prostaglandin D2 Receptor antibody - ab167348 from Abcam
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Anti-Prostaglandin D2 Receptor antibody - Cytoplasmic domain - ab140938 from Abcam
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Anti-MHC Class II D/DP Antibody - LS-C130762 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody - LS-C95996 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A503 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody - LS-C137384 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A8133 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (aa238-287) - LS-C145501 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (aa290-339) - LS-C135958 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (N-Terminus) IHC-plus™ - LS-A458 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody - LS-C146656 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (Glu301) - LS-C177423 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (aa263-312) - LS-C121022 from LifeSpan Bioscience
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Anti-Prostaglandin D2 Receptor Antibody (Extracellular Domain) IHC-plus™ - LS-A3279 from LifeSpan Bioscience
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DP1 Antibody - NB100-91736 from Novus Biologicals
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PTGDR Antibody - NBP1-71366 from Novus Biologicals
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PTGDR Antibody - NLS503 from Novus Biologicals
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PTGDR Antibody - NLS8133 from Novus Biologicals
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