GALNT2

Gene Symbol GALNT2
Entrez Gene 2590
Alt Symbol GalNAc-T2
Species Human
Gene Type protein-coding
Description polypeptide N-acetylgalactosaminyltransferase 2
Other Description UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)|polypeptide GalNAc transferase 2|pp-GaNTase 2
Swissprots A8K1Y3 Q9NPY4 B7Z8V8 Q10471 C5HU00
Accessions ACS13744 EAW69908 EAW69909 EAW69910 EAW69911 Q10471 AK025845 AK056187 AK097996 AK098468 AK290048 BAF82737 AK296886 BAH12448 AK300453 BAH13288 AK304029 BAH14094 BC041120 AAH41120 BC050583 BE328743 BF727269 BG773173 N53765 X85019 CAA59381 XM_011544154 XP_011542456 XM_011544155 XP_011542457 NM_001291866 NP_001278795 NM_004481 NP_004472 NR_120373
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. {ECO:0000269|PubMed:12438318, ECO:0000269|PubMed:16434399, ECO:0000269|PubMed:7592619, ECO:0000269|PubMed:9295285}.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9394011}; Single-pass type II membrane protein {ECO:0000269|PubMed:9394011}. Secreted {ECO:0000269|PubMed:9394011}. Note=Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:7592619}.
Top Pathways Mucin type O-Glycan biosynthesis

GalNAc-T2 (C-17) - sc-68511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GalNAc-T2 (E-17) - sc-68512 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GalNAc-T2 (G-16) - sc-68513 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GALNT2 antibody - ab102650 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab102650 staining GALNT2 in HeLa cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with 0.2% Triton X-100 and blocked with 1% BSA for 30 minutes at 25°C. Samples were incubated with primary antibody (1/50) for 1 hour at 25°C. A TRITC-conjugated goat anti-rabbit IgG monoclonal (1/250) was used as the secondary antibody.See Abreview

Anti-GALNT2 antibody - ab97741 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-GALNT2 antibody (ab97741) at 1/500 dilution + Molt-4 whole cell lysate at 30 µg

Anti-GALNT2 antibody [EPR9605(B)] - ab140637 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9605(B)
All lanes : Anti-GALNT2 antibody [EPR9605(B)] (ab140637) at 1/1000 dilutionLane 1 : A549 cell lysateLane 2 : HeLa cell lysateLane 3 : Human fetal heart lysateLane 4 : U87-MG cell lysateLane 5 : Human fetal liver lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit at 1/2000 dilution

Anti-GALNT2 antibody - C-terminal - ab140386 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GALNT2 antibody - C-terminal (ab140386) at 1 µg/ml + Rat kidney lysate at 10 µg

Anti-GALNT2 Antibody (aa26-53, AP) - LS-C257534 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody (aa26-53, APC) - LS-C257535 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody (aa26-53, Biotin) - LS-C257536 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody (aa26-53, FITC) - LS-C257537 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody (aa26-53, Azide-free, HRP) - LS-C257538 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody (aa26-53, PE) - LS-C257539 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody (aa32-62) - LS-C321545 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT2 Antibody - LS-C346137 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using GALNT2 antibody. Blue: DAPI for nuclear staining.

Anti-GALNT2 Antibody - LS-C155527 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Breast ca, using GALNT2 antibody at 1:250 dilution.

Anti-GALNT2 Antibody (aa26-53) - LS-C166354 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with GALNT2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-GALNT2 Antibody (aa55-369) - LS-C185588 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca using GALNT2 antibody at 1:250 dilution.

GALNT2 Antibody - NBP1-32394 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GALNT2 Antibody [NBP1-32394] - Sample (50 ug of whole cell lysate) A: Mouse white adipose tissue 7. 5% SDS PAGE; antibody diluted at 1:1000.

GALNT2 Antibody - AF7507 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of MOLT‑4 human acute lymphoblastic leukemia cell line, HeLa human cervical epithelial carcinoma cell line, and HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Polypeptide GalNac Transferase 2/GALNT2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7507) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Polypeptide GalNac Transferase 2/GALNT2 at approximately 65-70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

GALNT2 Antibody - NBP1-83394 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal

GALNT2 Antibody - H00002590-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

Anti-GALNT2 antibody produced in rabbit - SAB2700565 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GALNT2: <B>Cat. No. SAB2700565</B>: Immunohistochemical analysis of paraffin-embedded Breast carcinoma, using GALNT2 antibody at 1:500 dilution.

ANTI-GALNT2 (N-TERM) antibody produced in rabbit - SAB1303136 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>GALNT2 (N-term): <B>Cat. No. SAB1303136</B>: GALNT2 in Human brain tissue with GALNT2 antibody (N-term) at 5 μg/mL.

Anti-GALNT2 antibody produced in rabbit - HPA011222 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GALNT2: <B>Cat. No. HPA011222</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas shows strong granular cytoplasmic positivity in exocrine glandular cells.
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