Gene Symbol | GALNT2 |
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Entrez Gene | 2590 |
Alt Symbol | GalNAc-T2 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 2 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)|polypeptide GalNAc transferase 2|pp-GaNTase 2 |
Swissprots | A8K1Y3 Q9NPY4 B7Z8V8 Q10471 C5HU00 |
Accessions | ACS13744 EAW69908 EAW69909 EAW69910 EAW69911 Q10471 AK025845 AK056187 AK097996 AK098468 AK290048 BAF82737 AK296886 BAH12448 AK300453 BAH13288 AK304029 BAH14094 BC041120 AAH41120 BC050583 BE328743 BF727269 BG773173 N53765 X85019 CAA59381 XM_011544154 XP_011542456 XM_011544155 XP_011542457 NM_001291866 NP_001278795 NM_004481 NP_004472 NR_120373 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. {ECO:0000269|PubMed:12438318, ECO:0000269|PubMed:16434399, ECO:0000269|PubMed:7592619, ECO:0000269|PubMed:9295285}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9394011}; Single-pass type II membrane protein {ECO:0000269|PubMed:9394011}. Secreted {ECO:0000269|PubMed:9394011}. Note=Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:7592619}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-T2 (C-17) - sc-68511 from Santa Cruz Biotechnology
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GalNAc-T2 (E-17) - sc-68512 from Santa Cruz Biotechnology
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GalNAc-T2 (G-16) - sc-68513 from Santa Cruz Biotechnology
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Anti-GALNT2 antibody - ab102650 from Abcam
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Anti-GALNT2 antibody - ab97741 from Abcam
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Anti-GALNT2 antibody [EPR9605(B)] - ab140637 from Abcam
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Anti-GALNT2 antibody - C-terminal - ab140386 from Abcam
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Anti-GALNT2 Antibody (aa26-53, AP) - LS-C257534 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa26-53, APC) - LS-C257535 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa26-53, Biotin) - LS-C257536 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa26-53, FITC) - LS-C257537 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa26-53, Azide-free, HRP) - LS-C257538 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa26-53, PE) - LS-C257539 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa32-62) - LS-C321545 from LifeSpan Bioscience
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Anti-GALNT2 Antibody - LS-C346137 from LifeSpan Bioscience
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Anti-GALNT2 Antibody - LS-C155527 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa26-53) - LS-C166354 from LifeSpan Bioscience
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Anti-GALNT2 Antibody (aa55-369) - LS-C185588 from LifeSpan Bioscience
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GALNT2 Antibody - NBP1-32394 from Novus Biologicals
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GALNT2 Antibody - AF7507 from Novus Biologicals
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GALNT2 Antibody - NBP1-83394 from Novus Biologicals
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GALNT2 Antibody - H00002590-A01 from Novus Biologicals
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Anti-GALNT2 antibody produced in rabbit - SAB2700565 from Sigma-Aldrich
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ANTI-GALNT2 (N-TERM) antibody produced in rabbit - SAB1303136 from Sigma-Aldrich
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Anti-GALNT2 antibody produced in rabbit - HPA011222 from Sigma-Aldrich
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