GALNT2

Gene Symbol GALNT2
Entrez Gene 2590
Alt Symbol GalNAc-T2
Species Human
Gene Type protein-coding
Description polypeptide N-acetylgalactosaminyltransferase 2
Other Description UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)|polypeptide GalNAc transferase 2|pp-GaNTase 2
Swissprots A8K1Y3 Q9NPY4 B7Z8V8 Q10471 C5HU00
Accessions ACS13744 EAW69908 EAW69909 EAW69910 EAW69911 Q10471 AK025845 AK056187 AK097996 AK098468 AK290048 BAF82737 AK296886 BAH12448 AK300453 BAH13288 AK304029 BAH14094 BC041120 AAH41120 BC050583 BE328743 BF727269 BG773173 N53765 X85019 CAA59381 XM_011544154 XP_011542456 XM_011544155 XP_011542457 NM_001291866 NP_001278795 NM_004481 NP_004472 NR_120373
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. {ECO:0000269|PubMed:12438318, ECO:0000269|PubMed:16434399, ECO:0000269|PubMed:7592619, ECO:0000269|PubMed:9295285}.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9394011}; Single-pass type II membrane protein {ECO:0000269|PubMed:9394011}. Secreted {ECO:0000269|PubMed:9394011}. Note=Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:7592619}.
Top Pathways Mucin type O-Glycan biosynthesis

Human GALNT2 protein fragment - ab114957 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114957 at approximately 36.52kDa. Stained with Coomassie Blue.

GALNT2 Antibody Blocking Peptide - LS-E10074 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human GALNT2 Protein - H00002590-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

GALNT2-Antibody-N-term-Blocking-Peptide - BP9333a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human GALNT2, CF - 7507-GT-020 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Lys52-Gln571, with N-terminal 6-His tag

Human GALNT2 protein (His Tag) - orb138905 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 20 μg, 50 μg
Source Human Cells
Species Human
SDS-PAGE analysis of human GALNT2 protein (His Tag)

GALNT2 - H00002590-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

GALNT2 - H00002590-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

GALNT2 - P6179 from Acris Antibodies

Category Protein
Prices $840.00
Sizes 100 µg
Species Human

GALNT2 - P6183 from Acris Antibodies

Category Protein
Prices $840.00
Sizes 100 µg

GALNT2 fusion protein - Ag11562 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

GALNT2 fusion protein - ag11523 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human GALNT2 - GALNT2-27303TH from Creative Biomart

Category Protein
Source Wheat germ
Species Human

Recombinant Human GALNT2, His-tagged - GALNT2-13136H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human GALNT2, His tagged - GALNT2-229H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human GALNT2 - GALNT2-585H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Human GALNT2 / GalNAc-T2 Protein (His Tag) - 13764-H07H-20 from Sino Biological

Category Protein
Prices $178.00, $178.00
Sizes 20 µg, 50 µg
Source Human Cells
Species Human

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 2(GALNT2) - CSB-YP605995HU CSB-EP605995HU CSB-BP605995HU CSB-MP605995HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human GALNT2 Protein, CF - 7507-GT from R&D Systems

Category Protein
Prices $359.00
Sizes 20 µg
Source Mouse myeloma cell line, NS0-derived Lys52-Gln571, with N-terminal 6-His tag
Species Human

Recombinant Human GALNT2 (carrier-free) - 750402 from Biolegend

Category Protein
Prices $195.00, $325.00
Sizes 10 µg, 25 µg
Source Human GALNT2, amino acids (Lys52-Gln571) (Accession# NP_004472.1), was expressed with a N-terminal His tag in the 293E cell line.
Species Human
hGALNT2 is able to transfer GalNAc from UDP-GalNAc to mucin 10 (EA2) peptide in a dose dependent manner with an activity > 310 pmole/µg/min. The activity of hGALTN2 was determined by a phosphatase-coupled assay.

GALNT2 - TP307893 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
GALNT2

Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2), Recombinant Protein - MBS1443929 from MyBioSource

Category Protein
Prices $1,370.00, $1,370.00, $1,585.00, $1,585.00, $2,280.00, $2,280.00, $2,740.00, $2,740.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human GALNT2 / GalNAc-T2 Protein (His tag) - PKSH030561 from Elabscience

Category Protein
Source Human Cell
Species Human

GALNT2 Protein - NBP1-83394PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

GALNT2 Peptide, Human - M34GP06080H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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