SLC1A5

Gene Symbol	SLC1A5
Entrez Gene	6510
Alt Symbol	AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC
Species	Human
Gene Type	protein-coding
Description	solute carrier family 1 (neutral amino acid transporter), member 5
Other Description	ATB(0)|RD114 virus receptor|RD114/simian type D retrovirus receptor|baboon M7 virus receptor|neutral amino acid transporter B|neutral amino acid transporter B(0)|sodium-dependent neutral amino acid transporter type 2|solute carrier family 1 member 5
Swissprots	Q15758 A8K9H5 Q9UNP2 B4DWS4 Q9BWQ3 O95720 E9PC01 B4DR77 B7ZB81 D0EYG6 Q96RL9
Accessions	EAW57446 Q15758 AB209738 BAD92975 AF102826 AAD09812 AF105230 AAD09814 AF105423 AAD27806 AF334818 AAK77026 AK055630 AK125222 AK292690 BAF85379 AK293433 BAG56938 AK299137 BAG61189 AK301661 BAG63136 AK316546 BAH14917 BC000062 AAH00062 DA031076 DQ892148 ABM83074 DQ895345 ABM86271 GQ919058 ACX53626 U53347 AAC50629 XM_005259167 XP_005259224 NM_001145144 NP_001138616 NM_001145145 NP_001138617 NM_005628 NP_005619
Function	Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349). {ECO:0000269|PubMed:10051606, ECO:0000269|PubMed:10196349, ECO:0000269|PubMed:10708449, ECO:0000269|PubMed:23492904}.
Subcellular Location	Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity	Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
Top Pathways	Protein digestion and absorption, Central carbon metabolism in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC1A5 peptide - ab97988 from Abcam Category Peptide

SLC1A5 / ASCT2 Antibody Blocking Peptide - LS-E29546 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC1A5 / ASCT2 Antibody Blocking Peptide - LS-E29548 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC1A5 / ASCT2 Antibody Blocking Peptide - LS-E29547 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC1A5 / ASCT2 Antibody Blocking Peptide - LS-E10130 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC1A5 / ASCT2 Antibody Blocking Peptide - LS-E29753 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC1A5-Antibody-Center-Blocking-Peptide - BP9437c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC1A5 Blocking Peptide - 33R-2915 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RDRC fusion protein - Ag14182 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RDRC protein, GST-tagged - RDRC-2241H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Solute Carrier Family 1, Member 5 (SLC1A5) - RPE345Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Solute Carrier Family 1, Member 5 (SLC1A5) - RPE345Hu01 from Cloud-clone Category Protein Source E.coli Species Human

SLC1A5 Protein - abx164034 from Abbexa Category Protein Species Human, Mouse

SLC1A5 Protein - NBP1-89328PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SLC1A5 Recombinant Protein Antigen - NBP1-89327PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SLC1A5 Peptide, Human - M34GP14368H from Creative Peptides Category Peptide Source Synthetic. Species Human

SLC1A5 Recombinant Protein (OPCD07028) - OPCD07028 from Aviva Systems Biology Category Protein Source E.coli Species Human

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