SLC1A5

Gene Symbol SLC1A5
Entrez Gene 6510
Alt Symbol AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC
Species Human
Gene Type protein-coding
Description solute carrier family 1 (neutral amino acid transporter), member 5
Other Description ATB(0)|RD114 virus receptor|RD114/simian type D retrovirus receptor|baboon M7 virus receptor|neutral amino acid transporter B|neutral amino acid transporter B(0)|sodium-dependent neutral amino acid transporter type 2|solute carrier family 1 member 5
Swissprots Q15758 A8K9H5 Q9UNP2 B4DWS4 Q9BWQ3 O95720 E9PC01 B4DR77 B7ZB81 D0EYG6 Q96RL9
Accessions EAW57446 Q15758 AB209738 BAD92975 AF102826 AAD09812 AF105230 AAD09814 AF105423 AAD27806 AF334818 AAK77026 AK055630 AK125222 AK292690 BAF85379 AK293433 BAG56938 AK299137 BAG61189 AK301661 BAG63136 AK316546 BAH14917 BC000062 AAH00062 DA031076 DQ892148 ABM83074 DQ895345 ABM86271 GQ919058 ACX53626 U53347 AAC50629 XM_005259167 XP_005259224 NM_001145144 NP_001138616 NM_001145145 NP_001138617 NM_005628 NP_005619
Function Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349). {ECO:0000269|PubMed:10051606, ECO:0000269|PubMed:10196349, ECO:0000269|PubMed:10708449, ECO:0000269|PubMed:23492904}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
Top Pathways Protein digestion and absorption, Central carbon metabolism in cancer

ASCT2 CRISPR/Cas9 KO Plasmid (h) - sc-402795 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 HDR Plasmid (h) - sc-402795-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 Double Nickase Plasmid (h) - sc-402795-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 Double Nickase Plasmid (h2) - sc-402795-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 CRISPR Activation Plasmid (h) - sc-402795-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 CRISPR Activation Plasmid (h2) - sc-402795-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 Lentiviral Activation Particles (h) - sc-402795-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 Lentiviral Activation Particles (h2) - sc-402795-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASCT2 siRNA (h) - sc-60210 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASCT2 shRNA Plasmid (h) - sc-60210-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASCT2 shRNA (h) Lentiviral Particles - sc-60210-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19449 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19449 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05172 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05172

SLC1A5 siRNA (Human) - CRH4405 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC1A5 RNAi - H00006510-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SLC1A5 - MBS827427 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC1A5 (NM_005628.2) - SHH408944 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC1A5 siRNA - orb264907 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC1A5 shRNA Plasmid (Human) - CHH4405 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC1A5 miRNA 3'UTR clone - MiUTR3H-00237 from Creative biogene

Species Reactivities Human

SLC1A5 miRNA 3'UTR clone - MiUTR3H-00238 from Creative biogene

Species Reactivities Human

SLC1A5 miRNA 3'UTR clone - MiUTR3H-00239 from Creative biogene

Species Reactivities Human
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