C9

Gene Symbol C9
Entrez Gene 735
Alt Symbol ARMD15, C9D
Species Human
Gene Type protein-coding
Description complement component 9
Other Description complement component C9
Swissprots P02748
Accessions AAA51890 CAA69849 CAB66087 EAW55986 EAW55987 EAW55988 P02748 AK308045 BC020721 AAH20721 CB135741 CB157001 DQ891410 ABM82336 K02766 AAA51889 X02176 CAA26117 NM_001737 NP_001728
Function Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
Subcellular Location Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.
Tissue Specificity Plasma.
Top Pathways Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis

C5b-9 (aE11) - sc-58935 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

C9 (D-18) - sc-54579 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

C9 (I-19) - sc-54582 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

C9 (H-210) - sc-292164 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C9 (H-210): sc-292164. Western blot analysis of C9 expression in human liver tissue extract.

C9 (E-3) - sc-390000 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
C9 (E-3): sc-390000. Western blot analysis of C9 expression in human liver tissue extract.

C9 (64E9) - sc-69761 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
C9 (64E9): sc-69761. Western blot analysis of C9 purified from human plasma (A) and in human plasma (B).

Anti-C9 antibody - ab92690 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of C9 staining in Human Liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab92690, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-C9 antibody - ab118902 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis (Formalin-Fixed, Paraffin-Embedded) of Human Small Intestine, Vessels stained with ab118902 at 10 µg/ml

Anti-C9 antibody - ab137856 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of methanol-fixed HepG2 cells labelling C9 with ab137856 at 1/200 dilution. The image in the lower panel is costained with Hoechst 33342.

Anti-C9 antibody - ab71330 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-C9 antibody (ab71330) at 1 µg/ml + Placenta (Human) Tissue Lysate - adult normal tissue (ab29745) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-C9 antibody - ab64011 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C9 antibody (ab64011) at 1 µg/mlLane 1 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lane 2 : Placenta (Human) Tissue Lysate - adult normal tissue (ab29745)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-C9 antibody - ab67040 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C9 antibody (ab67040) at 1 µg/mlLane 1 : Human Plasma Total Protein Lysate Lane 2 : Placenta (Human) Tissue Lysate - adult normal tissue (ab29745)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-C9 antibody [53] - ab17931 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 53
Ab17931 staining human normal liver. Staining is localized to the cytoplasm.Left panel: with primary antibody at 2 ug/ml. Right panel: isotype control.Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 AR buffer, EDTA pH 9.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 minutes. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 minutes and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-C9 antibody [64E9] - ab52431 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 64E9
All lanes : Anti-C9 antibody [64E9] (ab52431) at 1/2000 dilutionLane 1 : Complement factor C9 isolated from human plasmaLane 2 : Human plasma

Anti-C9 antibody [aE11] - ab90801 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone aE11

Anti-C9 antibody [EPR11232] - ab168345 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11232
Immunoprecipitation: Western blot analysis on immunoprecipitation pellet from Human plasma cell lysate using ab168345 at a 1/10 dilution.

Anti-Complement C9 antibody [EPR11232-82] - ab173302 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11232-82
All lanes : Anti-Complement C9 antibody [EPR11232-82] (ab173302) at 1/1000 dilutionLane 1 : Human angioneoplasm lysateLane 2 : Human serum lysateLane 3 : Human plasma lysateLysates/proteins at 10 µg per lane.

Anti-Complement C9 Antibody - LS-C195782 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal

Anti-Complement C9 Antibody - LS-C196568 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-Complement C9 Antibody (clone X 197) - LS-C202491 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-Complement C9 Antibody (aa181-230) - LS-C119872 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO cells, using C9 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-Complement C9 Antibody (aa190-220, AP) - LS-C208195 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Complement C9 Antibody (aa190-220, APC) - LS-C208196 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Complement C9 Antibody (aa190-220, Biotin) - LS-C208197 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Complement C9 Antibody (aa190-220, Azide-free, HRP) - LS-C208199 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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