Gene Symbol | C9 |
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Entrez Gene | 735 |
Alt Symbol | ARMD15, C9D |
Species | Human |
Gene Type | protein-coding |
Description | complement component 9 |
Other Description | complement component C9 |
Swissprots | P02748 |
Accessions | AAA51890 CAA69849 CAB66087 EAW55986 EAW55987 EAW55988 P02748 AK308045 BC020721 AAH20721 CB135741 CB157001 DQ891410 ABM82336 K02766 AAA51889 X02176 CAA26117 NM_001737 NP_001728 |
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. |
Subcellular Location | Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore. |
Tissue Specificity | Plasma. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis |
C9 overexpression lysate - LY419774 from Acris Antibodies
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C9 293 Cell Lysate - 409263 from ABBIOTEC
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Complement Component C9 Overexpression Lysate (Native) - NBL1-08577 from Novus Biologicals
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C9 Over-expression Lysate Product - GWB-A98C50 from Genway Biotech
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Human Complement C9 Deficient Plasma (EDTA) - D910104 from AssayPro
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Human Complement C9 Deficient Plasma (EDTA) - D910105 from AssayPro
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Human Complement C9 Deficient Plasma (EDTA) - D910106 from AssayPro
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Human Complement C9 Deficient Plasma (Heparin) - D910107 from AssayPro
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Human Complement C9 Deficient Plasma (Heparin) - D910108 from AssayPro
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Human Complement C9 Deficient Plasma (Heparin) - D910109 from AssayPro
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Human Complement C9 Deficient Plasma (Sodium Citrate) - D910101 from AssayPro
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Human Complement C9 Deficient Plasma (Sodium Citrate) - D910102 from AssayPro
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Human Complement C9 Deficient Plasma (Sodium Citrate) - D910103 from AssayPro
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Human Complement C9 Deficient Serum - D910110 from AssayPro
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Human Complement C9 Deficient Serum - D910111 from AssayPro
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Human Complement C9 Deficient Serum - D910112 from AssayPro
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Panoply™ Human C9 Knockdown Stable Cell Line - CSC-DC002182 from Creative biogene
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