Gene Symbol | C9 |
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Entrez Gene | 735 |
Alt Symbol | ARMD15, C9D |
Species | Human |
Gene Type | protein-coding |
Description | complement component 9 |
Other Description | complement component C9 |
Swissprots | P02748 |
Accessions | AAA51890 CAA69849 CAB66087 EAW55986 EAW55987 EAW55988 P02748 AK308045 BC020721 AAH20721 CB135741 CB157001 DQ891410 ABM82336 K02766 AAA51889 X02176 CAA26117 NM_001737 NP_001728 |
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. |
Subcellular Location | Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore. |
Tissue Specificity | Plasma. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis |
C9 peptide - ab94838 from Abcam
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Human C9 full length protein - ab114199 from Abcam
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Human C9 full length protein - ab167803 from Abcam
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Human C9 full length protein - ab177730 from Abcam
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Human C9 peptide - ab71328 from Abcam
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Human C9 peptide - ab71329 from Abcam
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Complement Component C9 Recombinant Protein - H00000735-P01 from Novus Biologicals
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C9-Antibody-Center-Blocking-peptide - BP13782c from Abgent, a WuXi AppTec company
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C9 protein (His tag) - 80R-3755 from Fitzgerald
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Complement C9 protein - 32C-CP1050 from Fitzgerald
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Complement C9 (22-559, His-tag) - AR51442PU-N from Acris Antibodies
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Complement C9 (22-559, His-tag) - AR51442PU-S from Acris Antibodies
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Complement C9 - H00000735-P01-10 from Acris Antibodies
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Complement C9 - H00000735-P01-25 from Acris Antibodies
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C9, 22-559aa Human, His tag, E.coli - 01-P2622 from ARP American Research Products
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C9 fusion protein - Ag23137 from Proteintech Group
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C9 fusion protein - ag17999 from Proteintech Group
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Recombinant Human C9, GST-tagged - C9-26247TH from Creative Biomart
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Recombinant Human C9, His-tagged - C9-5126H from Creative Biomart
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Recombinant Human complement component 9, His-tagged - C9-525H from Creative Biomart
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Native Human Complement C9 - C9-58H from Creative Biomart
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Recombinant Complement Component 9 (C9) - RPB823Hu01 from Uscn Life Science Inc.
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Recombinant Complement Component 9 (C9) - RPB823Mu01 from Uscn Life Science Inc.
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Recombinant Complement Component 9 (C9) - RPB823Ra01 from Uscn Life Science Inc.
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Complement C9 Blocking Peptide - CBP1118 from Cohesion Biosciences
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