PITX2

Gene Symbol PITX2
Entrez Gene 5308
Alt Symbol ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
Species Human
Gene Type protein-coding
Description paired-like homeodomain 2
Other Description ALL1-responsive protein ARP1|all1-responsive gene 1|homeobox protein PITX2|paired-like homeodomain transcription factor 2|pituitary homeobox 2|rieg bicoid-related homeobox transcription factor 1|solurshin
Swissprots Q9BY17 O60579 Q99697 B2RA02 A8K6C6 Q3KQX9 O60580 B3KXS0 O60578
Accessions AAK15048 CDM63602 EAX06262 EAX06263 EAX06264 Q99697 AF048720 AAC39716 AF048721 AAC39717 AF048722 AAC39718 AK127829 BAG54582 AK291591 BAF84280 AK313987 BAG36699 BC013998 AAH13998 BC106010 AAI06011 BP372081 BX380370 DQ893426 ABM84352 DQ896741 ABM87740 U69961 AAC16257 XM_006714235 XP_006714298 XM_011532027 XP_011530329 NM_000325 NP_000316 NM_001204397 NP_001191326 NM_001204398 NP_001191327 NM_001204399 NP_001191328 NM_153426 NP_700475 NM_153427 NP_700476
Function Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.
Top Pathways TGF-beta signaling pathway

Pitx2 (H-1) - sc-390457 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pitx2 (H-1): sc-390457. Western blot analysis of Pitx2 expression in Y79 nuclear extract.

Pitx2 (H-80) - sc-33147 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pitx2 (H-80): sc-33147. Western blot analysis of Pitx2 expression in non-transfected: sc-117752 (A) and human Pitx2 transfected: sc-111686 (B) 293T whole cell lysates.

Pitx2 (C-16) - sc-8748 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pitx2 (C-16): sc-8748. Western blot analysis of Pitx2 expression in NIH/3T3 (A) and Y79 (B) nuclear extracts.

Anti-PITX2 antibody - ab32832 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PITX2 antibody (ab32832) at 2.5 µg/ml + HepG2 cell lysateSecondaryHRP conjugated anti Rabbit IgG at 1/50000 dilution

Anti-PITX2 antibody - ab55599 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55599 PITX2 antibody at 1ug/ml.

Anti-PITX2 antibody - ab98297 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PITX2 antibody (ab98297) at 1 µg/ml + Heart (Human) Tissue Lysate - adult normal tissue (ab29431) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PITX2 antibody - ab192495 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa41-71, FITC) - LS-C266398 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa41-71, Azide-free, HRP) - LS-C266399 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa41-71, PE) - LS-C266400 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (C-Terminus, AP) - LS-C281694 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (C-Terminus, APC) - LS-C281696 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (C-Terminus, Biotin) - LS-C281697 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (C-Terminus, FITC) - LS-C281699 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa42-71) - LS-C163743 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PITX2 Antibody western blot of CEM cell line lysates (35 ug/lane). The PITX2 antibody detected the PITX2 protein (arrow).

Anti-PITX2 / RGS Antibody (C-Terminus, Azide-free, HRP) - LS-C281700 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (C-Terminus, PE) - LS-C281701 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa41-71) - LS-C329974 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (C-Terminus) - LS-C328403 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody - LS-C341718 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (clone 2G6) - LS-C197910 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G6
Immunofluorescence of monoclonal antibody to PITX2 on HeLa cell . [antibody concentration 10 ug/ml]

Anti-PITX2 / RGS Antibody (aa122-151) - LS-C98142 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of HeLa cell stained with PITX2 Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with PITX2 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). PITX2 immunoreactivity is localized to Nucleus significantly.

Anti-PITX2 / RGS Antibody - LS-C9842 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa41-71, AP) - LS-C266395 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITX2 / RGS Antibody (aa41-71, APC) - LS-C266396 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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