PITX2

Gene Symbol PITX2
Entrez Gene 5308
Alt Symbol ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
Species Human
Gene Type protein-coding
Description paired-like homeodomain 2
Other Description ALL1-responsive protein ARP1|all1-responsive gene 1|homeobox protein PITX2|paired-like homeodomain transcription factor 2|pituitary homeobox 2|rieg bicoid-related homeobox transcription factor 1|solurshin
Swissprots Q9BY17 O60579 Q99697 B2RA02 A8K6C6 Q3KQX9 O60580 B3KXS0 O60578
Accessions AAK15048 CDM63602 EAX06262 EAX06263 EAX06264 Q99697 AF048720 AAC39716 AF048721 AAC39717 AF048722 AAC39718 AK127829 BAG54582 AK291591 BAF84280 AK313987 BAG36699 BC013998 AAH13998 BC106010 AAI06011 BP372081 BX380370 DQ893426 ABM84352 DQ896741 ABM87740 U69961 AAC16257 XM_006714235 XP_006714298 XM_011532027 XP_011530329 NM_000325 NP_000316 NM_001204397 NP_001191326 NM_001204398 NP_001191327 NM_001204399 NP_001191328 NM_153426 NP_700475 NM_153427 NP_700476
Function Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.
Top Pathways TGF-beta signaling pathway

Pitx2 CRISPR/Cas9 KO Plasmid (h) - sc-401426 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 HDR Plasmid (h) - sc-401426-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 Double Nickase Plasmid (h) - sc-401426-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 Double Nickase Plasmid (h2) - sc-401426-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 CRISPR Activation Plasmid (h) - sc-401426-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 CRISPR Activation Plasmid (h2) - sc-401426-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 Lentiviral Activation Particles (h) - sc-401426-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 Lentiviral Activation Particles (h2) - sc-401426-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pitx2 siRNA (h) - sc-44016 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pitx2 shRNA Plasmid (h) - sc-44016-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pitx2 shRNA (h) Lentiviral Particles - sc-44016-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PITX2 RNAi - H00005308-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PITX2 RNAi - H00005308-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU072181 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16845 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16845 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05895 from Sigma-Aldrich

Category miRNA

PITX2 siRNA (Human) - CRH3550 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PITX2 RNAi - H00005308-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PITX2 (NM_000325.5) - SHH376248 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PITX2(NM_000325.5) - SHR116580 from Creative biogene

Category siRNA
Species Reactivities Human

Human PITX2 siRNA - orb264052 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PITX2 shRNA Plasmid (Human) - CHH3550 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PITX2 miRNA 3'UTR clone - MiUTR1H-07934 from Creative biogene

Species Reactivities Human
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