Gene Symbol | PITX2 |
---|---|
Entrez Gene | 5308 |
Alt Symbol | ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS |
Species | Human |
Gene Type | protein-coding |
Description | paired-like homeodomain 2 |
Other Description | ALL1-responsive protein ARP1|all1-responsive gene 1|homeobox protein PITX2|paired-like homeodomain transcription factor 2|pituitary homeobox 2|rieg bicoid-related homeobox transcription factor 1|solurshin |
Swissprots | Q9BY17 O60579 Q99697 B2RA02 A8K6C6 Q3KQX9 O60580 B3KXS0 O60578 |
Accessions | AAK15048 CDM63602 EAX06262 EAX06263 EAX06264 Q99697 AF048720 AAC39716 AF048721 AAC39717 AF048722 AAC39718 AK127829 BAG54582 AK291591 BAF84280 AK313987 BAG36699 BC013998 AAH13998 BC106010 AAI06011 BP372081 BX380370 DQ893426 ABM84352 DQ896741 ABM87740 U69961 AAC16257 XM_006714235 XP_006714298 XM_011532027 XP_011530329 NM_000325 NP_000316 NM_001204397 NP_001191326 NM_001204398 NP_001191327 NM_001204399 NP_001191328 NM_153426 NP_700475 NM_153427 NP_700476 |
Function | Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Top Pathways | TGF-beta signaling pathway |
Human PITX2 full length protein - ab152611 from Abcam
|
||||||||||
Human PITX2 protein fragment - ab152612 from Abcam
|
||||||||||
Human PITX2 protein fragment - ab152613 from Abcam
|
||||||||||
Human PITX2 protein fragment - ab152614 from Abcam
|
||||||||||
PITX2 / RGS Antibody Blocking Peptide - LS-E2894 from LifeSpan Bioscience
|
||||||||||
PITX2 / RGS Antibody Blocking Peptide - LS-E3157 from LifeSpan Bioscience
|
||||||||||
PITX2 / RGS Antibody Blocking Peptide - LS-E11358 from LifeSpan Bioscience
|
||||||||||
PITX2 / RGS Antibody Blocking Peptide - LS-E13620 from LifeSpan Bioscience
|
||||||||||
Recombinant Human PITX2 Protein - H00005308-Q03 from Novus Biologicals
|
||||||||||
Recombinant Human PITX2 Protein - H00005308-P01 from Novus Biologicals
|
||||||||||
Recombinant Human PITX2 Protein - H00005308-Q02 from Novus Biologicals
|
||||||||||
Recombinant Human PITX2 Protein - H00005308-Q01 from Novus Biologicals
|
||||||||||
PITX2 Peptide - P0397 from Novus Biologicals
|
||||||||||
PITX2-Antibody-N-term-Blocking-peptide - BP14021a from Abgent, a WuXi AppTec company
|
||||||||||
PITX2-Antibody-C-term-Blocking-peptide - BP1429b from Abgent, a WuXi AppTec company
|
||||||||||
PITX2 - H00005308-P01 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q01-10 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q01-25 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q02 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q02-10 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q02-25 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q03-10 from Acris Antibodies
|
||||||||||
PITX2 - H00005308-Q03-25 from Acris Antibodies
|
||||||||||
PITX2 fusion protein - ag1583 from Proteintech Group
|
||||||||||
Recombinant Human Pituitary homeobox 2(PITX2) - CSB-YP860349HU CSB-EP860349HU CSB-BP860349HU CSB-MP860349HU from Cusabio
|