| Gene Symbol |
PITX2
|
| Entrez Gene |
5308
|
| Alt Symbol |
ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
paired-like homeodomain 2
|
| Other Description |
ALL1-responsive protein ARP1|all1-responsive gene 1|homeobox protein PITX2|paired-like homeodomain transcription factor 2|pituitary homeobox 2|rieg bicoid-related homeobox transcription factor 1|solurshin
|
| Swissprots |
Q9BY17 O60579 Q99697 B2RA02 A8K6C6 Q3KQX9 O60580 B3KXS0 O60578
|
| Accessions |
AAK15048 CDM63602 EAX06262 EAX06263 EAX06264 Q99697 AF048720 AAC39716 AF048721 AAC39717 AF048722 AAC39718 AK127829 BAG54582 AK291591 BAF84280 AK313987 BAG36699 BC013998 AAH13998 BC106010 AAI06011 BP372081 BX380370 DQ893426 ABM84352 DQ896741 ABM87740 U69961 AAC16257 XM_006714235 XP_006714298 XM_011532027 XP_011530329 NM_000325 NP_000316 NM_001204397 NP_001191326 NM_001204398 NP_001191327 NM_001204399 NP_001191328 NM_153426 NP_700475 NM_153427 NP_700476
|
| Function |
Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
TGF-beta signaling pathway
|