MFN1

Gene Symbol	MFN1
Entrez Gene	55669
Alt Symbol	hfzo1, hfzo2
Species	Human
Gene Type	protein-coding
Description	mitofusin 1
Other Description	fzo homolog|mitochondrial transmembrane GTPase FZO-2|mitochondrial transmembrane GTPase Fzo-1|mitofusin-1|putative transmembrane GTPase|transmembrane GTPase MFN1
Swissprots	O15323 Q9NWQ2 Q9BZB5 Q8IWA4 D3DNR6 O60639 B2RAR1
Accessions	EAW78406 EAW78407 EAW78408 EAW78409 EAW78410 EAW78411 EAW78412 Q8IWA4 AB043588 BAE16564 AB043589 BAE16565 AF054986 AAC09347 AF329637 AAK06840 AI656503 AK000700 BAA91327 AK314306 BAG36958 BC020661 AAH20661 BC040557 AAH40557 CR627379 CAH10476 EU832493 ACE87665 EU832574 ACE86976 JF432789 ADZ16006 U95822 AAB64220 XM_005247596 XP_005247653 XM_011512963 XP_011511265 NM_033540 NP_284941 NM_017927
Function	Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks. {ECO:0000269|PubMed:11181170, ECO:0000269|PubMed:12475957, ECO:0000269|PubMed:12759376, ECO:0000269|PubMed:23921378}.
Subcellular Location	Mitochondrion outer membrane {ECO:0000305|PubMed:11751411, ECO:0000305|PubMed:12759376}; Multi- pass membrane protein {ECO:0000305|PubMed:11751411, ECO:0000305|PubMed:12759376}.
Tissue Specificity	Ubiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers. {ECO:0000269|PubMed:11751411, ECO:0000269|PubMed:11950885, ECO:0000269|PubMed:12759376}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Mitofusin 1 full length protein - ab132635 from Abcam Category Protein Source Wheat germ Species Human

Human Mitofusin 1 protein fragment - ab153407 from Abcam Category Protein Source Wheat germ Species Human

Mitofusin 1 peptide - ab202006 from Abcam Category Peptide

Mitofusin 1 peptide - ab108243 from Abcam Category Peptide

MFN1 Antibody Blocking Peptide - LS-E3854 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MFN1 Antibody Blocking Peptide - LS-E21073 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MFN1 Antibody Blocking Peptide - LS-E21072 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MFN1 Antibody Blocking Peptide - LS-E26512 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Mitofusin 1 Protein - H00055669-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Mitofusin 1 Protein - H00055669-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MFN1-Antibody-Center-Blocking-Peptide - BP16037c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Mitofusin 1 Blocking Peptide - 33R-7768 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Mitofusin-1 - H00055669-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Mitofusin-1 - H00055669-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Mitofusin-1 - H00055669-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Mitofusin-1 - H00055669-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MFN1 Peptide - 7861P from ProSci Category Peptide Species Human

MFN1 fusion protein - ag4762 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MFN1 fusion protein - ag4890 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Mitofusin-1 - TP307184 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Mitofusin 1 (MFN1) - RPC619Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Mitofusin 1 (MFN1) - RPC619Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Mitofusin 1 (MFN1) - RPC619Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Mfn1 protein - orb86170 from Biorbyt Category Protein Prices $238.00 Sizes 500 µg

MFN1 Peptide, Human - M34GP09461H from Creative Peptides Category Peptide Source Synthetic. Species Human

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