Rnf6

Gene Symbol Rnf6
Entrez Gene 74132
Alt Symbol 1200013I08Rik, 5730419H05Rik, AA537053
Species Mouse
Gene Type protein-coding
Description ring finger protein (C3H2C3 type) 6
Other Description E3 ubiquitin-protein ligase RNF6|RLIM-like protein
Swissprots B2RRR0 Q8K565 Q9DBU5
Accessions EDL05800 EDL05801 EDL05802 Q9DBU5 AK004745 BAB23526 AK017576 AK029912 AK049503 AK150269 BAE29425 AK152106 BAE30953 AV586321 AY039004 AAK84435 BC138545 AAI38546 BY136428 BY323318 CX237430 XM_011241015 XP_011239317 NM_001256085 NP_001243014 NM_001256086 NP_001243015 NM_001256087 NP_001243016 NM_028774 NP_083050
Function E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator. {ECO:0000269|PubMed:11971979, ECO:0000269|PubMed:16204183}.
Subcellular Location Nucleus. Cytoplasm. Cell projection, axon. Nucleus, PML body. Note=Localizes to the PML nuclear bodies in Sertoli cells.
Tissue Specificity Widely expressed with higher expression in the testis in both germ cells and Sertoli cells. {ECO:0000269|PubMed:11971979}.

Recombinant Mouse E3 ubiquitin-protein ligase RNF6(Rnf6) - CSB-YP872050MO CSB-EP872050MO CSB-BP872050MO CSB-MP872050MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse RNF6 Protein - RNF6-14353M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

E3 ubiquitin-protein ligase RNF6 (Rnf6), Recombinant Protein - MBS1386278 from MyBioSource

Category Protein
Prices $1,470.00, $1,470.00, $1,695.00, $1,695.00, $2,500.00, $2,500.00, $2,940.00, $2,940.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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